Results 71 to 80 of about 4,485,922 (287)
Evaluation of arterial stiffness in cardiac surgical patients using applanation tonometry
Annals of Cardiac Anaesthesia, 2020 Context: Applanation tonometry enables the noninvasive analysis of arterial pressure wave morphology. Applanation tonometry provides the augmentation index (AIx, %), an index of arterial stiffness that partially reflects arterial-ventricular (A-V ...
Federico Franchi +7 more
doaj +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Pulse wave velocity and carotid atherosclerosis in White and Latino patients with hypertension
BMC Cardiovascular Disorders, 2011 Background Preventive cardiology has expanded beyond coronary heart disease towards prevention of a broader spectrum of cardiovascular diseases. Ethnic minorities are at proportionately greater risk for developing extracoronary vascular disease including
Karimkahani Elhum +7 more
doaj +1 more source
Modern methods for assessing cardiovascular risk in hypertension [PDF]
Ķazaķstannyṇ Klinikalyķ Medicinasy, 2016 Arterial hypertension is one of the most common diseases of the cardiovascular system, and is a leading risk factor for sudden death, both in Kazakhstan and abroad.
Gulnur Kerimkulova, Gulnar Zhussupova
doaj +1 more source
Increased augmentation index in patients with cystic fibrosis [PDF]
European Respiratory Journal, 2009 Increased large artery stiffness occurs in a range of inflammatory conditions indicating an ageing of the vasculature and additionally being an independent risk factor for cardiovascular events. We determined large artery parameters in adults with cystic fibrosis (CF).
J H, Hull +6 more
openaire +2 more sources
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Mìžnarodnij Endokrinologìčnij Žurnal, 2015 To study the effect of hypoglycemic therapy with combination of glimepiride and metformin SR during 12 weeks on carbohydrate and lipid metabolism parameters, changes in the adipokines level in blood plasma and parameters of arterial wall stiffness of ...
O.S. Larin, K.O. Zuiev, D.H. Kohut
doaj +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source