Results 61 to 70 of about 206,551 (266)

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie   +8 more
wiley   +1 more source

PENGEMBANGAN DESAIN E-DEDAKTIS MELALUI BAHAN AJAR BERBASIS PROJECT MENGGUNAKAN AUGMENTED REALITY

open access: yesAksioma: Jurnal Program Studi Pendidikan Matematika
Peranan bahan ajar yang sesuai dengan kebutuhan siswa dapat memudahkan siswa dalam memahami materi. Namun kondisinya di lapangan, bahan ajar pada pembelajaran matematika yang diterapkan masih belum sesuai dengan kebutuhannya.
Risma Amelia   +2 more
doaj   +1 more source

Augmented Reality for Identifying Maintainability Concerns during Design

open access: yesAdvances in Civil Engineering, 2019
In a building context, decisions made early in the design phase can have a major impact on maintainability of the resulting facility. Effectively leveraging the knowledge of facility management teams in the design stage can lead to improved ...
Imad A. Khalek   +2 more
doaj   +1 more source

ADOPT: An augmented set-based design framework with optimisation

open access: yesDesign Science, 2019
During the early stages of any system design, a thorough exploration of the design space can prove to be challenging and computationally expensive. The challenges are further exacerbated when dealing with complex systems, such as an aircraft, due to the ...
Alex Georgiades   +3 more
doaj   +1 more source

Long‐Term Neurologic Exam Findings in People Diagnosed and Treated During Acute HIV Infection

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Evaluate clinical and laboratory correlates of abnormal neurologic exam findings after acute HIV infection (AHI). Methods Participants from the RV254/SEARCH 010 cohort in Bangkok underwent standardized neurologic examinations at Weeks 0 (AHI), 12, 96, and 288 following antiretroviral therapy (ART).
Kathryn B. Holroyd   +118 more
wiley   +1 more source

Tools for an Augmented Design: quantitative virtual show&tell

open access: yesInteraction Design and Architecture(s), 2008
In this paper we describe a variant of the ‘show and tell’ method designed to be used in collaborative design processes. We will show that it works as a qualitative and, as well, as a quantitative aid to the design process, especially, but n o t
Carlo Giovannella, Andrea Camusi
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan   +7 more
wiley   +1 more source

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son   +3 more
wiley   +1 more source

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