Results 61 to 70 of about 769,952 (302)

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Augmented Reality Chemical Reaction with User-Centered Design

open access: yesMATEC Web of Conferences, 2018
One of chemistry is the chemical element that is represented by the symbol on the periodic table. The low level of activity, interest, and the result of chemistry learning in school is caused by the students generally having difficulty in solving ...
Nurpandi Finsa, Gumelar Agung
doaj   +1 more source

Augmented BIB Design-An Alternative Statistical Design in Germplasm Evaluation Trials

open access: yesJournal of Horticultural Sciences, 2008
Randomized Block Design (RBD) is commonly employed to evaluate a set of germplasm accessions (test treatments) along with local checks. In such a trial, if the test treatments under evaluation are more in number and the availability of the seeds is ...
R Venugopalan   +2 more
doaj   +1 more source

End-Users’ Augmented Reality Utilization for Architectural Design Review

open access: yesApplied Sciences, 2020
To effectively use augmented reality (AR) technology for end-user involved design collaboration, it is necessary to ensure the effectiveness of the AR system from the end-user’s perspective.
Jin Gang Lee   +3 more
doaj   +1 more source

The Development Application Promote Agritourism of Pakdee Farm with Augmented Reality Technology

open access: yesวารสารวิทยาการสารสนเทศและเทคโนโลยีประยุกต์, 2023
This research is a development of an application on the Android operating system. Its purposes are 1) to development application promote agritourism of Pakdee Farm with augmented reality technology and 2) to study the tourists’ satisfaction with this ...
Tirawat Sampaothong, Wiraiwan Sanchana
doaj   +1 more source

Both Generic Design and Different Forms of Designing [PDF]

open access: yes, 2006
This paper defends an augmented cognitively oriented "generic-design hypothesis": There are both significant similarities between the design activities implemented in different situations and crucial differences between these and other cognitive ...
Visser, Willemien
core   +3 more sources

Augmentation not Duplication [PDF]

open access: yesProceedings of the 2019 CHI Conference on Human Factors in Computing Systems, 2019
Digital-augmentation of print-media can provide contextually relevant audio, visual, or haptic content to supplement the static text and images. The design of such augmentation--its medium, quantity, frequency, content, and access technique--can have a significant impact on the reading experience.
Matjaz Kljun   +9 more
openaire   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Studying the Genetic Diversity of Barley Germplasm by Analyzing Agronomic Traits to Identify Superior Genotypes [PDF]

open access: yesپژوهشنامه اصلاح گیاهان زراعی
Extended Abstract Background: Barley (Hordeum vulgare L.) is recognized as one of the world's most significant cereals, playing a crucial role in providing both human food and animal feed.
Mostafa Haghpanah, Behrouz Vaezi
doaj  

Augmented reality supported model for the use of local data in architectural design

open access: yesInteraction Design and Architecture(s), 2021
This study presents a model that aims to enable better understanding of local site-specific data in the context of architectural design using augmented reality. It is developed by considering the necessities of local data in architectural design
Faruk Can Ünal, Yüksel Demir
doaj   +1 more source

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