Results 161 to 170 of about 48,863 (286)

Enhancing the Sensitivity of Colorimetric Aptasensor Through Cd2+‐Thymine Interactions in ssDNA Loops for Food Contaminant Detection

open access: yesFood Safety and Health, EarlyView.
This picture illustrates a novel aptamer‐based colorimetric assay, which demonstrates that high sensitivity, selectivity, and reliability for the rapid detection of cadmium ions (Cd2+) in water. Molecular dynamics (MD) simulations have revealed that the complexes are more stable, with Cd2+ binding more tightly to the thymine (T) within the aptamer loop.
Xuyan Li   +7 more
wiley   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

open access: yesIbrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

A dendrimer enhanced CRISPR/Cas12a performance for the evaluation of acidogenic capacity in cariogenic bacteria

open access: yesInterdisciplinary Medicine, EarlyView.
A CRISPR/Cas12a‐powered dendritic DNA nanostructure is assembled to create confined enzymatic microdomains, enabling ultrasensitive detection. Integrated into a paper‐based origami biosensor, it allows equipment‐free on‐site quantification of acidogenic pathogens for the early diagnosis of dental caries.
Yuan Zhang   +4 more
wiley   +1 more source

Long-Term Accumulation, Biological Effects and Toxicity of BSA-Coated Gold Nanoparticles in the Mouse Liver, Spleen, and Kidneys

open access: yesInternational Journal of Nanomedicine
Kristina Jakic,1 Michal Selc,1,2 Filip Razga,3 Veronika Nemethova,3 Petra Mazancova,3 Filip Havel,4,5 Michal Sramek,5 Monika Zarska,5 Jan Proska,4 Vlasta Masanova,6 Iveta Uhnakova,6 Peter Makovicky,7 Marta Novotova,8 Vit Vykoukal,9 Andrea Babelova1,2 ...
Jakic K   +14 more
doaj  

Development of Selective Plane Illumination Surface Enhanced Raman Scattering Spectral Microscopy for Improved Cellular Imaging

open access: yesJournal of Raman Spectroscopy, EarlyView.
Selective plane illumination (SPI) is combined with SERS spectral imaging to reduce background, improve image contrast, and enable improved spectroscopy from molecules on the surface of nanoparticles. This approach provides improved imaging and spectroscopy from nanoparticles in complex environments, such as biological cells.
Abigail E. Smith, Zachary D. Schultz
wiley   +1 more source

Reusable SERS Substrate Based on AuNP/PS‐b‐P2VP Nanocomposites With Photocatalytic Activity

open access: yesJournal of Raman Spectroscopy, EarlyView.
We developed a bifunctional SERS substrate by assembling AuNPs on PS‐b‐P2VP thin films, capable of both sensitive molecular detection and UV‐assisted self‐cleaning. The platform demonstrates excellent reusability over four adsorption–degradation cycles, driven by a hot‐hole‐mediated photocatalytic mechanism without semiconductors.
Moyra F. Vieira   +3 more
wiley   +1 more source

Eco-friendly AuNPs@rGO nanocomposite as a peroxidase-mimic for cholesterol detection. [PDF]

open access: yesRSC Adv
Al-Gethami W   +9 more
europepmc   +1 more source

Investigation of the laser fluence and wavelength dependence in surface‐assisted laser desorption/ionization mass spectrometry using gold nanoparticles

open access: yesRapid Communications in Mass Spectrometry, EarlyView.
Rationale Surface‐assisted laser desorption/ionization (SALDI) mass spectrometry (MS) builds on the use of nanostructured surfaces (e.g., coatings of colloidal nanoparticles) to promote analyte desorption and ionization. The SALDI process is believed to occur mainly through thermal processes, resulting from heating of the nanosubstrate upon absorption ...
Wendy H. Müller   +3 more
wiley   +1 more source

2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions

open access: yesSmall, EarlyView.
Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom   +6 more
wiley   +1 more source

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