Results 231 to 240 of about 580,897 (336)

Versatile Palladium‐Catalyzed C‐H Arylation of Fluoroarenes with 2‐Chloropyridine Derivatives

Chemistry – A European Journal, EarlyView.
Direct C─H arylation of fluoroarenes with 2‐chloropyridines is enabled by a simple Pd/SPhos system in isopropyl acetate. The method uses inexpensive reactants and shows broad scope and high yields. DFT computations explain reactivity and selectivity.
Federico Belnome, Péter P. Fehér, András Stirling, Csongor G. Németh, Tamás Hergert, György M. Keserű, Péter Ábrányi‐Balogh   +6 more
wiley   +1 more source

Elucidating the susceptibility genes between insomnia and migraine by integrating genetic data and transcriptomes. [PDF]

J Headache Pain
Wang T, Li J, Yao Y, Wang H, Zheng X.
europepmc   +1 more source

Notes Relative to the Sense of Smell in the Turkey Buzzard (Cathartes aura)

, 1888

openalex   +2 more sources

Precipitation of niobic acid from potassium niobate in sulphuric acid solution: A route to niobium oxide

The Canadian Journal of Chemical Engineering, EarlyView.
Graphical abstract illustrating the niobic acid precipitation process applied and the product obtained. Abstract This study investigates the precipitation of niobic acid (Nb2O5.nH2O) from potassium niobate solution with addition of sulphuric acid, and its subsequent thermal conversion into niobium oxide (Nb2O5). Thermodynamic modelling with PHREEQC and
Cássia R. Souza, Gabriela C. Silva, Isabel P. Silva, Frederico M. Penha, Sônia D. F. Rocha   +4 more
wiley   +1 more source

Aura

Kultúra és Közösség
openaire   +3 more sources

Vivid Dreams and Nightmares as an Adverse Effect of Beta-Blockers in the Treatment of Episodic Migraine. [PDF]

Case Rep Neurol Med
Silva-Rosas CR, Angus-Leppan H, Quijada AH, Briceño AG.   +3 more
europepmc   +1 more source

A Review of the Biochemical Diagnostic Biomarkers in Migraine: New Perspectives in Diagnostics. [PDF]

Pain Res Manag
Różycka K, Siwak N, Rucka A, Bielewicz J, Rejdak K.   +4 more
europepmc   +1 more source

A Phase 1, Randomized, Placebo‐Controlled, Multiple‐Dose, Double‐Blind Study to Evaluate and Compare the Pharmacokinetics and Safety of Rimegepant in Healthy Adult Japanese and Caucasian Individuals

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This Phase 1, randomized, placebo‐controlled, double‐blind study assessed the pharmacokinetic profile of rimegepant (25, 75, or 150 mg once daily for 14 days) in healthy Japanese and Caucasian adults. Exposures were modestly increased in Japanese participants compared with Caucasian participants following a single dose of rimegepant (Day 1 ...
Rajinder Bhardwaj, Chay Ngee Lim, Yinhua Li, Kyle T. Matschke, Richard Bertz, Robert Croop, Jing Liu   +6 more
wiley   +1 more source

Fu's Subcutaneous Needling treatment for migraine without aura: a randomized controlled trial protocol. [PDF]

Front Neurol
Guo W, Yang Y, Sun J.
europepmc   +1 more source

Integrated Population Pharmacokinetic, Pharmacodynamic, and Safety Analyses to Inform Dosage Selection in the Clinical Development of the ATR Inhibitor Tuvusertib

Clinical Pharmacology &Therapeutics, EarlyView.
We present model‐informed selection of the recommended dose for expansion (RDE) of investigational oral ATR inhibitor tuvusertib, by integrating clinical pharmacokinetics (PK), pharmacodynamics (PD), and safety data from DDRiver Solid Tumors 301 trial Part A1 (NCT04170153).
Jatinder Kaur Mukker, Paul Matthias Diderichsen, Farina Hellmann, Timothy A. Yap, Ruth Plummer, Anthony W. Tolcher, Johann S. de Bono, Ioannis Gounaris, Zoltan Szucs, Astrid Zimmermann, Irina Kareva, Jayaprakasam Bolleddula, Annick Seithel‐Keuth, Giuseppe Locatelli, Marta Enderlin, Christine Hicking, Anup Zutshi, Wei Gao, Rainer Strotmann, Lisa Benincosa, Karthik Venkatakrishnan   +20 more
wiley   +1 more source