Results 141 to 150 of about 5,328 (197)

Anti-staphylococcal activity of the auranofin-analogous PEt₃AuCl: antibacterial, anti-biofilm and anti-virulence effect on clinically relevant staphylococci. [PDF]

Front Cell Infect Microbiol
Mazzantini D, Amato B, Zineddu S, de Azevedo-França JA, Maisetta G, Ghelardi E, Esin S, Messori L, Batoni G.   +8 more
europepmc   +1 more source

LC-MS Evaluation of the Redox Trypanothione Balance in <i>Leishmania infantum</i> Parasites. [PDF]

Antioxidants (Basel)
Villarubias T, Royo J, Perio P, Bourgeade-Delmas S, Sudor J, Valentin A, Terrisse AD, Reybier K.   +7 more
europepmc   +1 more source

The PKCι-β-arrestin2 axis disrupts SORLA retrograde trafficking, driving its degradation and amyloid pathology in Alzheimer's disease. [PDF]

Mol Neurodegener
Rehman H, Yan S, Saggu S, Aida M, Zhang F, Shu Y, Jones A, Trang A, Dew E, Zhi W, Claeboe ET, Baucum AJ, Wu G, Jiao K, Wang Q.   +14 more
europepmc   +1 more source

Role of thioredoxin reductase (TrxB) in oxidative stress response of <i>Francisella tularensis</i> live vaccine strain. [PDF]

J Bacteriol
Higgs M, Ma Z, Centone A, Bakshi CS, Malik M.   +4 more
europepmc   +1 more source

Genome-Wide CRISPR Screening Reveals That mTOR Inhibition Initiates Ferritinophagy and Ferroptosis in Head and Neck Cancer. [PDF]

Cancer Res
Koshizuka K, Wu X, Sato K, Vo PTT, Murawska GM, Ishikawa T, Wang Z, Molinolo AA, Dennis EA, Nathan CO, Mali P, Gutkind JS.   +11 more
europepmc   +1 more source

Repurposing Auranofin for Oncology and Beyond: A Brief Overview of Clinical Trials as Mono- and Combination Therapy. [PDF]

Pharmaceuticals (Basel)
Giorgini D, Chiaverini L, Viviano M, Belvedere R, Salerno S, Baglini E, Da Settimo F, Marzo T, Taliani S, Barresi E.   +9 more
europepmc   +1 more source

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Auranofin

Clinics in Rheumatic Diseases, 1984
It has been widely accepted for a number of years that chrysotherapy is a valuable therapeutic agent in the treatment of progressive rheumatoid disease. This therapeutic benefit has, to some extent, been offset by the potential toxicity associated with gold compounds. The development of a gold compound with a greater therapeutic to toxicity ratio would
M, Ferrari, M T, Piro
  +7 more sources

Repurposing of auranofin: Thioredoxin reductase remains a primary target of the drug

Biochimie, 2019
Auranofin is a gold (1)-containing compound used for the treatment of rheumatic arthritis. Auranofin has anticancer activity in animal models and is approved for clinical trials for lung and ovarian carcinomas.
Xiaonan Zhang, Karthik Selvaraju, Amir Ata Saei   +2 more
exaly   +2 more sources