Results 1 to 10 of about 633 (121)

Gold(I) ion and the phosphine ligand are necessary for the anti-Toxoplasma gondii activity of auranofin [PDF]

open access: yesMicrobiology Spectrum
Auranofin, an FDA-approved drug for rheumatoid arthritis, has emerged as a promising antiparasitic medication in recent years. The gold(I) ion in auranofin is postulated to be responsible for its antiparasitic activity.
C. I. Ma   +11 more
doaj   +2 more sources

MicroRNA strand ratio disarray promotes temozolomide resistance in glioblastoma [PDF]

open access: yesCellular & Molecular Biology Letters
Background Disarray in microRNA (miRNA) strand selection is associated with multiple tumors. However, the mechanisms underlying miRNA strand selection-driven temozolomide (TMZ) resistance in glioblastoma (GBM) remain unexplored. Approach and results Here,
Fangfang Shen   +10 more
doaj   +2 more sources

Molecular structure of aurothioglucose: a comprehensive computational study

open access: yesTetrahedron, 2015
Abstract In order to investigate the molecular structure of aurothioglucose (ATG), six stable, well-known conformations of glucopyranose (Gp) have been computed and compared with Gp, thioglucopyranose (TGp), monomeric aurothioglucose (MATG), and dimeric aurothioglucose (DATG) models. The study has been performed using two DFT approaches.
Jerzy Leszczynski, Sedat Karabulut
exaly   +4 more sources

Effectiveness and safety of oral corticosteroids in the treatment of rheumatoid arthritis: a systematic review

open access: yesRevista Brasileira de Farmácia Hospitalar e Serviços de Saúde, 2022
Objective: This systematic review analyzed the effectiveness and the safety of oral corticosteroids in the treatment of rheumatoid arthritis. Method: The search sources were Cochrane (CENTRAL), MEDLINE, EMBASE, CINAHL, Web of Science, among other; in ...
Rodrigo S. IWAMI   +3 more
doaj   +1 more source

Thrombocytopenia due to aurothioglucose, sulphasalazine, and hydroxychloroquine. [PDF]

open access: yesAnnals of the Rheumatic Diseases, 1990
A 56 year old woman with rheumatoid arthritis developed relapsing thrombocytopenia during successive treatments with aurothioglucose, sulphasalazine, and hydroxychloroquine. The presence of IgM or IgG antibodies or immune complexes reactive with autologous platelets could not be shown.
M J, Wijnands   +4 more
openaire   +2 more sources

Aurothioglucose Inhibits Murine Thioredoxin Reductase Activity In Vivo [PDF]

open access: yesThe Journal of Nutrition, 1999
Gold (I)-containing compounds, including aurothioglucose (ATG), are potent in vitro inhibitors of several selenocysteine-containing enzymes. Gold compounds have also been shown to potentiate the virulence of several viruses in mice, including coxsackievirus, implicated as a possible infectious agent in Keshan disease.
A D, Smith   +3 more
openaire   +2 more sources

Hepatotoxicity with aurothioglucose therapy [PDF]

open access: yesArthritis & Rheumatism, 1984
P J, Lowthian   +2 more
openaire   +2 more sources

Aurothioglucose obesity in the mouse.

open access: yesThe Yale journal of biology and medicine, 2003
R H, DRACHMAN, J, TEPPERMAN
openaire   +1 more source
Some of the next articles are maybe not open access.

Aurothioglucose overdosage in five patients with rheumatoid arthritis

Clinical Rheumatology, 1987
Five patients with active seronegative, rheumatoid arthritis, HLA-DR3 negative, received inadvertently 250 to 500 mg of aurothioglucose instead of their usual weekly dose, during standard remission-inducing chrysotherapy. Subsequently a rapid and sustained clinical remission appeared in all five patients.
P Langevitz, Langevitz P, M Pras
exaly   +3 more sources

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