Results 1 to 10 of about 633 (125)

Gold(I) ion and the phosphine ligand are necessary for the anti-Toxoplasma gondii activity of auranofin [PDF]

Microbiology Spectrum
Auranofin, an FDA-approved drug for rheumatoid arthritis, has emerged as a promising antiparasitic medication in recent years. The gold(I) ion in auranofin is postulated to be responsible for its antiparasitic activity.
C. I. Ma, J. A. Tirtorahardjo, S. S. Schweizer, J. Zhang, Z. Fang, L. Xing, M. Xu, D. A. Herman, M. T. Kleinman, B. S. McCullough, A. M. Barrios, R. M. Andrade   +11 more
doaj   +2 more sources

MicroRNA strand ratio disarray promotes temozolomide resistance in glioblastoma [PDF]

Cellular & Molecular Biology Letters
Background Disarray in microRNA (miRNA) strand selection is associated with multiple tumors. However, the mechanisms underlying miRNA strand selection-driven temozolomide (TMZ) resistance in glioblastoma (GBM) remain unexplored. Approach and results Here,
Fangfang Shen, Pengfei Wu, Zelian Li, Minglong Yang, Zhuolun Li, Yunfeng Nan, Qinglin Yang, Yuanfei Wang, Xuedong Li, Ying Ye, Jinpeng Wang   +10 more
doaj   +2 more sources

Molecular structure of aurothioglucose: a comprehensive computational study

Tetrahedron, 2015
Abstract In order to investigate the molecular structure of aurothioglucose (ATG), six stable, well-known conformations of glucopyranose (Gp) have been computed and compared with Gp, thioglucopyranose (TGp), monomeric aurothioglucose (MATG), and dimeric aurothioglucose (DATG) models. The study has been performed using two DFT approaches.
Sedat Karabulut, Jerzy Leszczynski
exaly   +4 more sources

The zinc finger domains of PARP ‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose [PDF]

FEBS Letters
Bashtanova U, Duer MJ.
exaly   +2 more sources

Aurothioglucose enhances proangiogenic pathway activation in lungs from room air and hyperoxia-exposed newborn mice

American Journal of Physiology - Lung Cellular and Molecular Physiology, 2020
Katelyn Dunigan-Russell, Stephanie B Wall, Anusha Sridharan   +2 more
exaly   +2 more sources

Effectiveness and safety of oral corticosteroids in the treatment of rheumatoid arthritis: a systematic review

Revista Brasileira de Farmácia Hospitalar e Serviços de Saúde, 2022
Objective: This systematic review analyzed the effectiveness and the safety of oral corticosteroids in the treatment of rheumatoid arthritis. Method: The search sources were Cochrane (CENTRAL), MEDLINE, EMBASE, CINAHL, Web of Science, among other; in ...
Rodrigo S. IWAMI, Mariana D. MOURA, Flavia B. SORRILHA, Cristiane C. BERGAMASCHI   +3 more
doaj   +1 more source

Thrombocytopenia due to aurothioglucose, sulphasalazine, and hydroxychloroquine. [PDF]

Annals of the Rheumatic Diseases, 1990
A 56 year old woman with rheumatoid arthritis developed relapsing thrombocytopenia during successive treatments with aurothioglucose, sulphasalazine, and hydroxychloroquine. The presence of IgM or IgG antibodies or immune complexes reactive with autologous platelets could not be shown.
M J, Wijnands, W A, Allebes, A M, Boerbooms, L B, van de Putte, P L, van Riel   +4 more
openaire   +2 more sources

Aurothioglucose Inhibits Murine Thioredoxin Reductase Activity In Vivo [PDF]

The Journal of Nutrition, 1999
Gold (I)-containing compounds, including aurothioglucose (ATG), are potent in vitro inhibitors of several selenocysteine-containing enzymes. Gold compounds have also been shown to potentiate the virulence of several viruses in mice, including coxsackievirus, implicated as a possible infectious agent in Keshan disease.
A D, Smith, C A, Guidry, V C, Morris, O A, Levander   +3 more
openaire   +2 more sources

Production of Metallic Alloy Nanowires and Particles Templated Using Tomato Mosaic Virus (ToMV). [PDF]

Nanomaterials (Basel), 2023
Shah SN, Heddle JG, Evans DJ, Lomonossoff GP.   +3 more
europepmc   +1 more source

Autoimmune Hypoglycemia With Anti-Insulin Autoantibodies in an Eighty-One-Year-Old Woman Without Apparent Risk Factors. [PDF]

AACE Clin Case Rep, 2023
Kumar V, Gala D, Rafi I, Shah M, Marowa S, Kaul D, Lukose S, Kazeem S.   +7 more
europepmc   +1 more source