Results 141 to 150 of about 142,807 (311)

Inestabilidad Cromosómica Inducida por el Inhibidor de la Proteína Quinasa Aurora A

, 2014
Ana Maritza Erazo Milla
openalex   +2 more sources

Concomitant 5‐Aminosalicylic Acid Does Not Affect the Efficacy of Janus Kinase Inhibitors in Ulcerative Colitis

Clinical Pharmacology &Therapeutics, EarlyView.
We evaluated whether concomitant 5‐aminosalicylic acid (5‐ASA) influences clinical remission in patients with ulcerative colitis (UC) receiving Janus kinase inhibitors (JAKi). In this retrospective, multicenter cohort study, UC patients receiving tofacitinib (n = 181), upadacitinib (n = 313), or filgotinib (n = 139) were included.
Antonio Tursi, Andrea Pasta, Walter Elisei, Brigida Barberio, Giammarco Mocci, Giovanni Maconi, Antonietta Gerarda Gravina, Raffaele Pellegrino, Giorgia Bodini, Edoardo Vincenzo Savarino, Alfredo Papa, Italian Network for Inflammatory Bowel Diseases (IN‐IBD), Davide G. Ribaldone, Antonio Ferronato, Greta Lorenzon, Davide Checchin, Francesca Lambroglia, Francesco Ferrara, Carla Felice, Giovanni Cataletti, Giorgia Bodini, Andrea Pasta, Giovanni Aragona, Patrizia Perazzo, Federica Gaiani, Stefano Kayali, Fabio Cortellini, Francesco Costa, Lorenzo Bertani, Antonella Scarcelli, Mariaelena Serio, Emanuele Bendia, Laura Bolognini, Daniele Balducci, Claudia Quatraccioni, Francesco Martini, Michele Montori, Simona Piergallini, Francesca Maria Onidi, Paolo Usai Satta, Giorgia Orrù, Raffaele Colucci, Francesco Bachetti, Gabrio Bassotti, Elisabetta Antonelli, Costantino Zampaletta, Giulia Rocco, Carlotta Sacchi, Franco Scaldaferri, Daniele Napolitano, Roberto Faggiani, Michela Di Fonzo, Rita Monterubbianesi, Cristiano Pagnini, Maria Giovanna Graziani, Maria Carla Di Paolo, Roberta Pica, Maddalena Zippi, Andrea Cocco, Claudio Cassieri, Roberto Lorenzetti, Gian Marco Giorgetti, Valeria Clemente, Patrizio Scarozza, Girolamo Bevevino, Giulia Zerboni, Federico Iacopini, Giacomo Forti, Laurino Grossi, Serafina Fiorella, Giovanni Lombardi, Marta Patturelli, Giuliana Vespere, Silvia Sedda, Vittorio D’Onofrio, Leonardo De Luca, Caterina Mucherino, Elvira D’Antonio, Laura Montesano, Pietro Capone, Guido Daniele Villani, Antonio Cuomo, Laura Donnarumma, Nicola Della Valle, Giuseppe Pranzo, Paolo Tonti, Viviana Neve, Libera Fanigliulo, Leonardo Allegretta, Alessia Immacolata Cazzato, Stefano Scorza, Manuela Marzo, Ileana Luppino, Francesco Luzza, Rocco Spagnuolo, Stefano Rodinò, Ladislava Sebkova, Antonio De Medici, Domenico Catarella, Dario D’Agostino, Elisabetta Di Bartolo   +100 more
wiley   +1 more source

Superior Intracellular Detection of Cytokines, Transcription Factors, and Phosphoproteins by CyTOF Compared With Fluorescent Cytometry

Cytometry Part A, EarlyView.
ABSTRACT Unraveling biological complexity, such as immune subset distribution in infectious disease(s), autoimmunity, or tumor heterogeneity, requires technologies capable of single‐cell proteomic analysis such as flow cytometry. Surface phenotyping alone is often insufficient, as interrogating functional capacity is required to determine cellular ...
Michael J. Cohen, Erika L. Smith‐Mahoney, Madison Bailey, Ling Wang, Lauren J. Tracey, Laura Polanco, David King, Christina Loh, Amedeo J. Cappione III, Anna C. Belkina, Jennifer E. Snyder‐Cappione   +10 more
wiley   +1 more source

Editorial: Cold-ion populations and cold-electron populations in the Earth’s magnetosphere and their impact on the system

Frontiers in Astronomy and Space Sciences, 2023
Joseph E. Borovsky, Gian Luca Delzanno, Elena A. Kronberg, Cecilia Norgren   +3 more
doaj   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source

Tumour specific HORMAD1 expression perturbs mitotic arrest and drives sensitivity to mitotic kinase inhibitors. [PDF]

Nat Commun
Walker C, Kollarovic G, Weekes D, Trendell J, Hoffmann RM, Martin A, Ferro R, Navarro-Llinas B, Hitchen L, Pardo Calvo M, Balan N, Kemp H, Carroll A, Davidson K, Nath S, D'Uonno N, Lu R, Starling C, Otten M, Iakobachvili N, Marcozzi C, Rahman I, Quist J, Yu L, Krastev DB, Amodeo V, Roxanis I, Grigoriadis A, Bayliss R, Choudhary J, Haider S, Pines J, Pettitt SJ, Lord CJ, Tutt ANJ.   +34 more
europepmc   +1 more source

DESIGN SYNTHESIS OF NOVEL ACRIDINE TAGGED PYRAZOLE DERIVATIVES AS AURORA KINASE INHIBITORS

, 2020
HARATHI PERKA, D SATYAVATI, DEEPAK REDDY GADE, VIVEKANANDA BOYA, RAJENDRA PRASAD VVS   +4 more
openalex   +1 more source

Inferences Concerning Auroras [PDF]

Proceedings of the National Academy of Sciences, 1916
openaire   +3 more sources

Shifting baselines increase the risk of misinterpreting biodiversity trends

Ecography, EarlyView.
Ecological studies quantifying the impact of land‐use change on biodiversity may be sensitive to the choice of reference points – or baselines – particularly when sampling across human land‐use gradients and other space‐for‐time comparisons. Much depends on whether the chosen baseline has already undergone shifts in species composition because of ...
Ariane Dellavalle, Adam J. M. Devenish, Crinan Jarrett, Nathaniel N. D. Annorbah, Augustus Asamoah, Kwame Boafo, Poppy E. Lane, Jake Owen, Alexandra C. Morel, Mark F. Hulme, Andreanna J. Welch, Ken Norris, Fiona J. Sanderson, Joseph A. Tobias   +13 more
wiley   +1 more source

Covalent Peptide-Based N-Myc/Aurora-A Inhibitors Bearing Sulfonyl Fluoride Warheads. [PDF]

J Pept Sci
Dawber RS, Gimenez D, Preston GW, Wright MH, Bayliss R, Warriner SL, Wilson AJ.   +6 more
europepmc   +1 more source