Results 151 to 160 of about 454 (264)

Effect of time to palliative epilepsy surgery on outcomes

Epilepsia, EarlyView.
Abstract Objective Epilepsy duration is a modifiable risk factor in the outcome of definitive epilepsy surgery; however, an analogous effect in palliative procedures has not been shown. We reviewed the Pediatric Epilepsy Surgery Database data for an association between epilepsy duration and seizure reduction in palliative procedures.
Robert M. Crutcher, David E. Horvat, Avery R. Caraway, Kristen H. Arredondo, Taylor J. Abel, Nitin Agarwal, Allyson L. Alexander, Dallas Michael Armstrong, Kurtis I. Auguste, Danilo Bernardo, Jeffrey Bolton, David Bonda, Dewi Frances Depositario‐Cabacar, Krista Eschbach, William D. Gaillard, Aran Groves, Jason S. Hauptman, Pradeep K. Javarayee, Cemal Karakas, Andrew T. Knox, Jenny J. Lin, Patricia E. McGoldrick, Derryl J. Miller, Edward John Novotny, Adam P. Ostendorf, Pilar D. Pichon, Shilpa B. Reddy, Debopam Samanta, Rani K. Singh, Janelle L. Wagner, Steven M. Wolf, Lily C. Wong‐Kisiel, Fernando N. Galan, M. Scott Perry, Michael A. Ciliberto   +34 more
wiley   +1 more source

A Global Collaborative Comparison of SARS-CoV-2 Antigenicity Across 15 Laboratories. [PDF]

Viruses
Brangel P, Tureli S, Mühlemann B, Liechti N, Zysset D, Engler O, Hunger-Glaser I, Ghiga I, Mattiuzzo G, Eckerle I, Bekliz M, Rössler A, Schmitt MM, Knabl L, Kimpel J, Tort LFL, de Araujo MF, de Oliveira ACA, Caetano BC, Siqueira MM, Budt M, Gensch JM, Wolff T, Hassan T, Selvaraj FA, Hermanus T, Kgagudi P, Crowther C, Richardson SI, Bhiman JN, Moore PL, Cheng SMS, Li JKC, Poon LLM, Peiris M, Corman VM, Drosten C, Lai L, Hunsawong T, Rungrojcharoenkit K, Lohachanakul J, Sigal A, Khan K, Thiel V, Barut GT, Ebert N, Mykytyn AZ, Owusu Donkor I, Aboagye JO, Nartey PA, Van Kerkhove MD, Cunningham J, Haagmans BL, Suthar MS, Smith D, Subissi L.   +55 more
europepmc   +1 more source

Epilepsy‐associated SCN2A‐L1342P mutation drives network hyperexcitability and widespread transcriptomic changes in human cortical organoids

Epilepsia, EarlyView.
Abstract Objective SCN2A pathogenic mutations, such as the recurrent heterozygous Nav1.2‐L1342P, are monogenic causes of epilepsy. In this human‐induced pluripotent stem cell–derived model system, we aim to investigate the molecular and cellular mechanisms underlying SCN2A‐L1342P‐associated pathology. Methods Using a human male induced pluripotent stem
Maria I. Olivero‐Acosta, Morgan Robinson, Zhefu Que, Zaiyang Zhang, Karen V. Salazar‐Salazar, Hope Elizabeth Harlow, Vinayak Shankar, Seoyeon Hong, Muhan Wang, Conrad M. Otterbacher, Hina Kadono, Manasi Halurkar, Harish Kothandaraman, Nadia Atallah Lanman, Trang Nguyen, Kyle Wettschurack, Benjamin Zirkle, Layan Yunis, Ningren Cui, Xiaoling Chen, Jingliang Zhang, Jiaxiang Wu, William C. Skarnes, Chongli Yuan, Feng Guo, Megan Abbott, Yang Yang   +26 more
wiley   +1 more source

Wandering of the auroral oval 41,000 years ago. [PDF]

Sci Adv
Mukhopadhyay A, Panovska S, Garvey R, Liemohn MW, Ganjushkina N, Brenner A, Usoskin I, Balikhin M, Welling DT.   +8 more
europepmc   +1 more source

Changes in effectiveness and safety in patients with Lennox–Gastaut syndrome transitioning from the fenfluramine randomized controlled trial to open‐label extension study

Epilepsia Open, EarlyView.
This graphical abstract provides an overview of the content from this post hoc analysis describing the trajectories of fenfluramine effectiveness and safety, along with dose changes over time, in patients with Lennox‐Gastaut syndrome. Abstract In the phase 3 randomized controlled trial (RCT; NCT03355209) of fenfluramine in Lennox–Gastaut syndrome (LGS),
Rima Nabbout, Orrin Devinsky, Lieven Lagae, Ingrid E. Scheffer, Renzo Guerrini, Joseph Sullivan, Antonio Gil‐Nagel, Sameer M. Zuberi, Kate Riney, Patrick Healy, Jayne Abraham, Rebecca Zhang Roper, Mélanie Langlois, Amélie Lothe, Kelly G. Knupp   +14 more
wiley   +1 more source

Exceptionally gigantic aurora in the polar cap on a day when the solar wind almost disappeared. [PDF]

Sci Adv
Hosokawa K, Kataoka R, Tsuda TT, Ogawa Y, Taguchi S, Zhang Y, Paxton LJ.   +6 more
europepmc   +1 more source

Pulsed wave tissue Doppler imaging of the left ventricle in foals: Feasibility, inter‐ and intra‐observer variability and wave pattern over the first days of life

Equine Veterinary Journal, EarlyView.
Abstract Background Tissue Doppler imaging (TDI) may improve the assessment of myocardial function in neonatal foals. Objectives To document the feasibility of left ventricular pulsed wave (PW) TDI, inter‐ and intra‐observer variability and wave pattern over the first 5 days of life. Study Design Prospective observational study.
Fernanda Timbó D'el Rey Dantas, Gayle Hallowell, Carolina Castagnetti, Giovanni Romito, Laura Menchetti, Aurora Mannini, Aliai Lanci, Jole Mariella, Francesca Freccero   +8 more
wiley   +1 more source

Multiple time-scale beats in aurora: precise orchestration via magnetospheric chorus waves. [PDF]

Sci Rep, 2020
Hosokawa K, Miyoshi Y, Ozaki M, Oyama SI, Ogawa Y, Kurita S, Kasahara Y, Kasaba Y, Yagitani S, Matsuda S, Tsuchiya F, Kumamoto A, Kataoka R, Shiokawa K, Raita T, Turunen E, Takashima T, Shinohara I, Fujii R.   +18 more
europepmc   +1 more source

Global upper-atmospheric heating on Jupiter by the polar aurorae. [PDF]

Nature, 2021
O'Donoghue J, Moore L, Bhakyapaibul T, Melin H, Stallard T, Connerney JEP, Tao C.   +6 more
europepmc   +1 more source

Breeding switchgrass for reduced nitrogen demand

Grassland Research, EarlyView.
Breeding has improved switchgrass biomass yield, but productivity is still heavily dependent on nitrogen fertilizer application. The genetic diversity needed to improve nitrogen use efficiency of switchgrass remains underused, mainly because of the slow and laborious breeding process, thus leaving the crop's high nitrogen demand as a major barrier to ...
Michael D. Casler, Prabin Bajgain
wiley   +1 more source