Results 81 to 90 of about 454 (264)
VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis
Advanced Science, EarlyView.Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang +7 more
wiley +1 more source
Climatological predictions of the auroral zone locations driven by moderate and severe space weather events. [PDF]
Sci Rep, 2023 Maffei S +6 more
europepmc +1 more source
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Chronic rhinosinusitis (CRS) and olfactory dysfunction (OD) are highly prevalent among people with cystic fibrosis (PwCF) and negatively impact quality of life. The 40‐item Smell Identification Test (SIT) is widely used to assess psychophysical olfaction, but a CF‐specific minimal clinically important difference (MCID) has not been ...
Eugene Oh +34 more
wiley +1 more source
Simulations of Electron Beam Interactions in Brown Dwarf Atmospheres
The Astrophysical JournalOver two decades ago, the first detection of electron cyclotron maser instability radio emission from a brown dwarf confirmed the presence of aurorally precipitating electrons on these objects.
Anna Zuckerman +4 more
doaj +1 more source
Hepatology, EarlyView., 2022 Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai +29 more
wiley +1 more source
Vertical and Temporal H3+ Structure at the Auroral Footprint of Io
The Planetary Science JournalWe report the first observation of the vertical and temporal structure of the H _3 ^+ emission at the auroral footprint of Io, as observed by Juno/JIRAM.
A. Mura +12 more
doaj +1 more source
Resolved imaging confirms a radiation belt around an ultracool dwarf. [PDF]
Nature, 2023 Kao MM +3 more
europepmc +1 more source
Hepatology, EarlyView., 2022 Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel +93 more
wiley +1 more source
Astronomy & AstrophysicsVariability monitoring provides unparalleled insights into the atmospheric processes of brown dwarfs and directly imaged exoplanets. Inhomogeneous clouds, aurorae, and magnetic spots have all been postulated as potential drivers of variability.
O’Toole C. +7 more
doaj +1 more source