Results 61 to 70 of about 454 (264)
DictyosteliumAurora Kinase Has Properties of both Aurora A and Aurora B Kinases
Eukaryotic Cell, 2008 ABSTRACTAurora kinases are highly conserved proteins with important roles in mitosis. Metazoans contain two kinases, Aurora A and B, which contribute distinct functions at the spindle poles and the equatorial region respectively. It is not currently known whether the specialized functions of the two kinases arose after their duplication in animal cells
Li, Hui +5 more
openaire +2 more sources
Advanced Science, EarlyView.Upon mitotic entry, RTN4 relocalizes to the pericentrosomal region, forming a more tubular ER network around centrosomes. CDK1‐mediated phosphorylation of RTN4 increases its interaction with Rab11 GTPase, facilitating dynein‐dependent transport of RTN4 to the pericentrosomal region.
Xiangyu Xu +9 more
wiley +1 more source
Advanced Science, EarlyView.Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung +39 more
wiley +1 more source
Advanced Science, EarlyView.We bioengineered a new approach methodology of generating Germinal Center Organoids that self‐organize from human blood‐derived immune cells. These immune organoids reproduce key features of humoral immunity, IgG production, and plasmablast emergence.
Bhumi Suthar +4 more
wiley +1 more source
Antarctic Record, 1971 This is a preliminary report of the sections of aurora and geomagnetism of the wintering party of the 10th Japanese Antarctic Research Expedition in 1969-1970. Among various observations carried out in these sections, VLF emission phenomena are described
Kanji HAYASHI
doaj +1 more source
Advanced Science, EarlyView.A minimally invasive optical window enables stable, long‐term imaging of peripheral nerves in vivo at single‐axon resolution. Dynamic processes of degeneration, regeneration, and cellular remodeling are visualized across multiple time scales within the same nerve region, providing a unique platform to study a variety of anatomical and molecular events ...
Igor D. Luzhansky +15 more
wiley +1 more source
Autoantigen mRNA‐LNP Vaccination Drives Therapeutic Efficacy in Preclinical Models for Autoimmunity
Advanced Science, EarlyView.Systemic and intramuscular delivery of autoantigen mRNA via lipid nanoparticles reprograms antigen‐presenting cells toward a mature, homeostatic state, driving antigen‐specific T cell exhaustion and providing therapeutic efficacy across autoimmune disease models.
Paulien Baeten +30 more
wiley +1 more source
Isolable C‐Phosphonio‐Boratavinyl Anion
Angewandte Chemie, EarlyView.A persistent C‐phosphonio boratavinyl anion was successfully synthesized. This boron‐containing vinyl lithium, featuring a vinyl carbon with an excessively high negative charge, exhibits remarkable nucleophilic and basic character, which was demonstrated by the result of a rapid reaction with H2 at RT.
Huihui Xu +7 more
wiley +2 more sources
Saturn’s Recurrent Auroral Flashes in the Equinoctial Campaign
The Astrophysical JournalThe past decades of Cassini’s investigation around Saturn have revealed the frequent occurrence of ∼1 hr quasiperiodic (QP) signatures in the in situ magnetic field and plasma measurements and plasma wave observations. Saturn’s aurora, as the response to
Tianshu Qin +4 more
doaj +1 more source