Gold(I) ion and the phosphine ligand are necessary for the anti-Toxoplasma gondii activity of auranofin [PDF]
Microbiology SpectrumAuranofin, an FDA-approved drug for rheumatoid arthritis, has emerged as a promising antiparasitic medication in recent years. The gold(I) ion in auranofin is postulated to be responsible for its antiparasitic activity.
C. I. Ma +11 more
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MicroRNA strand ratio disarray promotes temozolomide resistance in glioblastoma [PDF]
Cellular & Molecular Biology LettersBackground Disarray in microRNA (miRNA) strand selection is associated with multiple tumors. However, the mechanisms underlying miRNA strand selection-driven temozolomide (TMZ) resistance in glioblastoma (GBM) remain unexplored. Approach and results Here,
Fangfang Shen +10 more
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Revista Brasileira de Farmácia Hospitalar e Serviços de Saúde, 2022 Objective: This systematic review analyzed the effectiveness and the safety of oral corticosteroids in the treatment of rheumatoid arthritis. Method: The search sources were Cochrane (CENTRAL), MEDLINE, EMBASE, CINAHL, Web of Science, among other; in ...
Rodrigo S. IWAMI +3 more
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Aurothioglucose Inhibits Murine Thioredoxin Reductase Activity In Vivo [PDF]
The Journal of Nutrition, 1999 Gold (I)-containing compounds, including aurothioglucose (ATG), are potent in vitro inhibitors of several selenocysteine-containing enzymes. Gold compounds have also been shown to potentiate the virulence of several viruses in mice, including coxsackievirus, implicated as a possible infectious agent in Keshan disease.
A D, Smith +3 more
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Thrombocytopenia due to aurothioglucose, sulphasalazine, and hydroxychloroquine. [PDF]
Annals of the Rheumatic Diseases, 1990 A 56 year old woman with rheumatoid arthritis developed relapsing thrombocytopenia during successive treatments with aurothioglucose, sulphasalazine, and hydroxychloroquine. The presence of IgM or IgG antibodies or immune complexes reactive with autologous platelets could not be shown.
M J, Wijnands +4 more
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Molecular structure of aurothioglucose: a comprehensive computational study
Tetrahedron, 2015 Abstract In order to investigate the molecular structure of aurothioglucose (ATG), six stable, well-known conformations of glucopyranose (Gp) have been computed and compared with Gp, thioglucopyranose (TGp), monomeric aurothioglucose (MATG), and dimeric aurothioglucose (DATG) models. The study has been performed using two DFT approaches.
Sedat Karabulut, Jerzy Leszczynski
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Production of Metallic Alloy Nanowires and Particles Templated Using Tomato Mosaic Virus (ToMV). [PDF]
Nanomaterials (Basel), 2023 Shah SN +3 more
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Autoimmune Hypoglycemia With Anti-Insulin Autoantibodies in an Eighty-One-Year-Old Woman Without Apparent Risk Factors. [PDF]
AACE Clin Case Rep, 2023 Kumar V +7 more
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Some aspects of the diagnosis and treatment of eosinophilic granuloma in cats. [PDF]
J Vet Res, 2023 Omelchenko H +6 more
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Delivery of the selenoprotein thioredoxin reductase 1 to mammalian cells. [PDF]
Front Mol Biosci, 2022 Wright DE +3 more
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