Results 21 to 30 of about 67,988 (149)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Comparative Analysis of British, Austrian, and Greek Consular Networks in the Romanian Danube Ports (1850 – 1900) [PDF]
Codrul CosminuluiIn the second half of the 19th century, a growing interest from prominent European actors in the strategic and economic potential of the Romanian Danube ports became increasingly evident.
Ionel Constantin MITEA
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Научно-аналитический вестник Института Европы РАН, 2018 The article considers the most important stages in the formation of a new format of Central European cooperation with the participation of Austria, Slovakia and the Czech Republic.
Mariya Rusakova
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Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Türkiyat MecmuasıOttoman historiography boasts an extensive body of work, particularly on political and military developments. Among these, the 1683 Vienna Campaign holds a pivotal place as a turning point in Ottoman history, marking the end of the empire’s expansion ...
Metin Aydar
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Julian Dunajewski jako polityk
Acta Universitatis Lodziensis: Folia Historica, 2017 Artykuł opisuje życie Juliana Dunajewskiego, jednego z najważniejszych polskich polityków drugiej połowy XIX w. Autor przedstawia skrócony życiorys profesora, jego karierę naukową i najważniejsze dzieła.
Tomasz Olejnik
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Österreichisches Religionspädagogisches Forum, 2023 Auf der Basis von 15 Gruppeninterviews 2021-22 mit Jugendlichen in säkularen,alevitischen, sunnitischen, protestantischen und katholischen Gruppen in Tirol,Vorarlberg, Oberösterreich und Niederösterreich, wird nach dem empirischen Ortreligiöser Vielfalt ...
Lehmann, Karsten +10 more
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source