Results 91 to 100 of about 5,046 (296)

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Authenticated Encryption Schemes with Message Linkages for Message Flows

open access: yes, 2012
[[abstract]]Two efficient authenticated encryption schemes with message linkages are proposed. One is a basic scheme, that it has the better performance in comparison with the all previously proposed schemes in terms of the communication and the ...
Tseng, Yuh-Min; Jan, Jinn-Ke; Chien, Hung-Yu   +1 more
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

On Leakage-Resilient Authenticated Encryption with Decryption Leakages

open access: yesIACR Transactions on Symmetric Cryptology, 2017
At CCS 2015, Pereira et al. introduced a pragmatic model enabling the study of leakage-resilient symmetric cryptographic primitives based on the minimal use of a leak-free component.
Francesco Berti   +3 more
doaj   +1 more source

A New Convertible Authenticated Encryption Scheme Based on the ElGamal Cryptosystem

open access: yes, 2012
[[abstract]]"A convertible authenticated encryption scheme allows a designated receiver to retrieve an authenticated ciphertext and convert the authenticated ciphertext into an ordinary signature.
李正吉;Lee, Cheng-Chi;黃明祥;Hwang, Min-Shiang
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Authenticated Encryption: How Reordering can Impact Performance [PDF]

open access: yes, 2014
In this work, we look at authenticated encryption schemes from a new perspective. As opposed to focusing solely on the {\em ``security\u27\u27} implications of the different methods for constructing authenticated encryption schemes, we investigate the ...
Basel Alomair
core  

THE HARDWARE PERFORMANCE OF AUTHENTICATED ENCRYPTION MODES [PDF]

open access: yes, 2020
Authenticated encryption has long been a vital operation in cryptography by its ability to provide confidentiality, integrity and authenticity at the same time.
Hristina Mihajloska
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

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