Results 31 to 40 of about 2,799 (211)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Subverting Telegram’s End-to-End Encryption

IACR Transactions on Symmetric Cryptology, 2023
Telegram is a popular secure messaging service with third biggest user base as of 2021. In this paper, we analyze the security of Telegram’s end-to-end encryption (E2EE) protocol in presence of mass-surveillance.
Benoît Cogliati, Jordan Ethan, Ashwin Jha   +2 more
doaj   +1 more source

Authenticated Encryption Implementation Scheme Based on Tweakable Grouping [PDF]

Jisuanji gongcheng, 2020
The authentication encryption algorithm is difficult to generate the indistinguishability of Chosen Plaintext Attack(CPA) in practical application.Therefore,an improved encryption scheme of adjustable authentication is proposed by means of hardware ...
ZHAO Fuxiang
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

How to Implement Authenticated Encryption on XTS-Enabled Devices

IACR Transactions on Symmetric Cryptology
XTS is a block cipher mode for storage encryption. IEEE and NIST have standardized it, and it is widely deployed in real-world applications, including FileVault2, Bitlocker, and dm-crypt.
Akiko Inoue, Kazuhiko Minematsu, Rei Ueno, Naofumi Homma   +3 more
doaj   +1 more source

A Security Analysis of Deoxys and its Internal Tweakable Block Ciphers

IACR Transactions on Symmetric Cryptology, 2017
In this article, we provide the first independent security analysis of Deoxys, a third-round authenticated encryption candidate of the CAESAR competition, and its internal tweakable block ciphers Deoxys-BC-256 and Deoxys-BC-384.
Carlos Cid, Tao Huang, Thomas Peyrin, Yu Sasaki, Ling Song   +4 more
doaj   +1 more source

Key Assignment Schemes with Authenticated Encryption, revisited

IACR Transactions on Symmetric Cryptology, 2020
A popular cryptographic option to implement Hierarchical Access Control in organizations is to combine a key assignment scheme with a symmetric encryption scheme.
Jeroen Pijnenburg, Bertram Poettering
doaj   +1 more source