Results 51 to 60 of about 5,046 (296)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

How to Implement Authenticated Encryption on XTS-Enabled Devices

open access: yesIACR Transactions on Symmetric Cryptology
XTS is a block cipher mode for storage encryption. IEEE and NIST have standardized it, and it is widely deployed in real-world applications, including FileVault2, Bitlocker, and dm-crypt.
Akiko Inoue   +3 more
doaj   +1 more source

A Security Analysis of Deoxys and its Internal Tweakable Block Ciphers

open access: yesIACR Transactions on Symmetric Cryptology, 2017
In this article, we provide the first independent security analysis of Deoxys, a third-round authenticated encryption candidate of the CAESAR competition, and its internal tweakable block ciphers Deoxys-BC-256 and Deoxys-BC-384.
Carlos Cid   +4 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Key Assignment Schemes with Authenticated Encryption, revisited

open access: yesIACR Transactions on Symmetric Cryptology, 2020
A popular cryptographic option to implement Hierarchical Access Control in organizations is to combine a key assignment scheme with a symmetric encryption scheme.
Jeroen Pijnenburg, Bertram Poettering
doaj   +1 more source

Improvement of Tseng et al's authenticated encryption scheme

open access: yes, 2010
An attack is proposed to show that Tseng et al.’s authenticated encryption scheme is not secure enough to provide confidentiality for messages.
黃心嘉; Hwang, Shin-jia
core   +1 more source

Interactive Encryption and Message Authentication [PDF]

open access: yes, 2014
Public-Key Encryption (PKE) and Message Authentication (PKMA, aka as digital signatures) are fundamental cryptographic primitives. Traditionally, both notions are defined as non-interactive (i.e., single-message). In this work, we initiate rigorous study of (possibly) interactive PKE and PKMA schemes.
Yevgeniy Dodis, Dario Fiore 0001
openaire   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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