Results 91 to 100 of about 319,627 (296)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

An anonymous credential-based efficient staged dual-chain authentication protocol for satellite–earth links

open access: yesJournal of King Saud University: Computer and Information Sciences
With the rapid development of satellite technology, the privacy authentication problem is becoming increasingly prominent. To solve the low efficiency of user authentication caused by frequent switching of the satellite-earth link and possible identity ...
Yanshuo Zhang   +5 more
doaj   +1 more source

Research and Mass Deployment of Non-cognitive Authentication Strategy Based on Campus Wireless Network

open access: yesITM Web of Conferences, 2018
With the rapid development of Internet +, the dependence on wireless networks and wireless terminals are increasing. Campus wireless network has become the main network of teachers and students in campus on the internet. As there are uneven clients and a
Huangfu Dapeng   +3 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

How to Authenticate a Device? Formal Authentication Models for M2M Communications Defending against Ghost Compromising Attack

open access: yesInternational Journal of Distributed Sensor Networks, 2013
In Machine-to-Machine (M2M) communications, authentication of a device is of upmost importance for applications of Internet of Things. As traditional authentication schemes always assume the presence of a person, most authentication technologies cannot ...
Wei Ren, Linchen Yu, Liangli Ma, Yi Ren
doaj   +1 more source

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