Results 21 to 30 of about 55,577 (266)

The downregulation of NCXs is positively correlated with the prognosis of stage II–IV colon cancer

open access: yesWorld Journal of Surgical Oncology, 2021
Purpose Colon cancer (CC) is a very common gastrointestinal tumor that is prone to invasion and metastasis in the late stage. This study aims to observe the expression of Na+/Ca2+ exchangers (NCXs) and analyze the correlation between NCXs and the ...
Zhixiu Xia, Changliang Wang, Hong Zhang
doaj   +1 more source

Single-nucleus transcriptomics reveal the morphogenesis and artemisinin biosynthesis in Artemisia annua glandular trichomes

open access: yesNature Communications
Artemisinin, the key antimalarial drug, is synthesized in Artemisia annua glandular secretory trichomes (GSTs), yet their development and artemisinin’s precise cellular origins are unclear.
Minghui Zhang   +7 more
doaj   +1 more source

Glandular trichomes: the factory of artemisinin biosynthesis

open access: yesMedicinal Plant Biology
Plant glandular trichomes serve as crucial secretory organs, responsible for the production, modification, and storage of various vital secondary metabolites, including medicinal natural products, while also playing a role in plant defense mechanisms ...
Qiaojuan Zhao   +3 more
doaj   +1 more source

Authenticity as authentication

open access: yesPopular Music, 2002
This article argues for the prematurity of any dismissal of the notion of authenticity as meaningful within popular music discourse. It synthesises a range of views as to how authenticity is constructed, and offers a tri-partite typology dependent on asking who, rather than what, is being authenticated.
openaire   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Negotiating Authentic Objects and Authentic Selves [PDF]

open access: yesJournal of Material Culture, 2010
Our understanding of authenticity in the material world is characterized by a problematic dichotomy between materialist and constructivist perspectives. Neither explains why people find the issue of authenticity so compelling, nor how it is experienced and negotiated in practice.
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Performance of three handheld NIR spectrometers for predicting grass silage quality

open access: yesBiotechnologie, Agronomie, Société et Environnement, 2022
Description of the subject. Feed is the main variable cost in dairy farming. More efficient use of forage resources is one way to reduce production costs.
Juan Antonio Fernández Pierna   +7 more
doaj  

A Novel Cross-Layer Authentication Protocol for the Internet of Things

open access: yesIEEE Access, 2020
An innovative cross-layer authentication protocol that integrates cryptography-based authentication and physical layer authentication (PLA) is proposed for massive cellular Internet of things (IoT) systems.
Yonggu Lee   +3 more
doaj   +1 more source

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