Results 61 to 70 of about 55,577 (266)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Reliable and Cost-Effective QuEChERS–UHPLC–MS/MS Method for the Simultaneous Analysis of Ten Mycotoxins in Dendrobium Officinale: A Study on Food-Medicine Homology Quality Control

Journal of Analytical Methods in Chemistry
This study developed a method for simultaneously detecting 10 mycotoxins in Dendrobium officinale using the QuEChERS technique combined with ultra-high-performance liquid chromatography–tandem mass spectrometry (UHPLC–MS/MS). The method was optimized for
Zejun Wang, Qingcheng Wang, Fei Xu, Linhua Wang, Jingjing Liang, Qing Shen, Shunyuan Guo   +6 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Fighting counterfeit pesticides using mid-infrared spectroscopy and chemometrics

Green Analytical Chemistry
The use of pesticides, which are essential for agriculture and public health, poses risks when they are of out of specification or counterfeited, as they may be ineffective, toxic, or harmful to human and animal health, crops, and the environment ...
Juan Antonio Fernández Pierna, Quentin Arnould, Delphine Delhotte, Pierre Hucorne, Gilles Rousseau, Jérôme Bodart, Vincent Baeten, Olivier Pigeon   +7 more
doaj   +1 more source

Authenticity and Communication

, 2016
Authenticity is not an absolute and constant quality inherent in an object or an experience; it is constructed in the process of research. Actors inscribe and attribute it to both material objects and subjective processes like communication and consumption. This article from the research group seeks on the one hand to reflect on the historical scope of
Fless, F, Graf, B, Dally, O, Franke, U, Gerbich, C, Lengyel, D, Knaut, M, Naeser, C, Savoy, B, Steinmuller, LK, Steudtner, K, Taschner, M, Toulouse, C, Weber, S   +13 more
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Research on efficient cross trust-domain group authentication with conditional privacy of vehicle platoon under blockchian architecture

Tongxin xuebao, 2023
In order to balance the security and efficiency of vehicle platoon cross trust-domain identity authentication, an efficient cross trust-domain group authentication scheme with conditional privacy of vehicle platoon under blockchian architecture was ...
Yingjie XIA, Siyu ZHU, Xuejiao LIU
doaj   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Efficient authentication scheme for cross-trust domain of IoV based on double-layer shard blockchain

Tongxin xuebao, 2023
To solve the problems of poor scalability, slow synchronization of authentication information, and high authentication overhead in cross-trust domain message authentication in the Internet of vehicles (IoV), an efficient authentication scheme for cross ...
Xuejiao LIU, Qiang ZHONG, Yingjie XIA
doaj   +2 more sources

A validated real-time PCR test for simultaneous detection of Gallus gallus and Meleagris gallopavo in feed instead of an impossible poultry test

Biotechnologie, Agronomie, Société et Environnement
Description of the subject. Use of all processed animal proteins (PAPs) in animal feeds was banned in the EU due to the outbreak of bovine spongiform encephalopathy (BSE).
Aline Marien, Olivier Fumière, Alexandra Roetschi, Julien Maljean, Gilbert Berben   +4 more
doaj   +1 more source