Results 111 to 120 of about 36,662 (307)
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
SOAP: A Social Authentication Protocol
CoRRISBN:978-1-939133-44 ...
Felix Linker, David A. Basin
openaire +3 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
A Security Enhanced Authentication Protocol
2024 5th International Conference on Intelligent Communication Technologies and Virtual Mobile Networks (ICICV)Internet of Things (IoT) have gained popularity in recent times. With an increase in the number of IoT devices, security and privacy vulnerabilities are also increasing. For sensitive domains like healthcare and industrial sectors, such vulnerabilities can cause havoc.
Sai Sreekar Vankayalapati +2 more
openaire +2 more sources
Selection of EAP-authentication methods in WLANs
, 2007 IEEE 802.1X is a key part of IEEE802.11i. By employing Extensible Authentication Protocol (EAP) it supports a variety of upper layer authentication methods each with different benefits and drawbacks.
Owens, TJ, Ali, KM
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
网络与信息安全学报A critical component of cybersecurity protection in the internet of vehicles (IoV) was identity authentication. However, many existing authentication schemes were plagued by low efficiency and incompatibility with domestic cryptographic algorithms.
SU Binting, FANG He, XU Li
doaj
Secure Multiround Authentication Protocols [PDF]
, 1995 Gemmell and Naor proposed a new protocol for unconditionally secure authentication of long messages. However Gehrmann showed that the proof of the security of the protocol was incorrect. Here we generalize the multiround protocol model. We prove the security of a 3-round protocol and give for this case a new easy implementable construction which has a ...
openaire +1 more source
Mobility management across converged IP-based heterogeneous access networks
, 2010 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 8/2/2010.In order to satisfy customer demand for a high performance “global” mobility service, network operators (ISPs, carriers, mobile operators, etc ...
Mussabbir, Qazi Bouland
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source