Results 71 to 80 of about 2,279,222 (327)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

A Secure Authentication Protocol for Internet of Vehicles

IEEE Access, 2019
An Internet of Vehicles (IoV) allows forming a self-organized network and broadcasting messages for the vehicles on roads. However, as the data are transmitted in an insecure network, it is essential to use an authentication mechanism to protect the ...
Chien‐Ming Chen, Bin Xiang, Yining Liu, King-Hang Wang   +3 more
semanticscholar   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

An efficient authentication and key agreement protocol for IoT-enabled devices in distributed cloud computing architecture

EURASIP Journal on Wireless Communications and Networking, 2021
With the widespread use of Internet of Things and cloud computing in smart cities, various security and privacy challenges may be encountered.The most basic problem is authentication between each application, such as participating users, IoT devices ...
Huihui Huang, Siqi Lu, Zehui Wu, Qiang Wei   +3 more
doaj   +1 more source

Authentication over Internet Protocol

Bulletin of the Polish Academy of Sciences Technical Sciences, 2020
Defending against DoS (denial of service) attacks has become a great challenge, especially for institutions that provide access to their services in the public network. State-of-the-art identity concealing tools and vast number of computers connected to the network require ensuring appropriate means for entities at risk to enable defence from the ...
Ł. Apiecionek, J.M. Czerniak, M. Romantowski, D. Ewald, B. Tsizh, H. Zarzycki, W.T. Dobrosielski   +6 more
openaire   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

ZERO KNOWLEDGE PASSWORD AUTHENTICATION PROTOCOL

International Journal of Communication Networks and Security, 2012
In many applications, the password is sent as cleartext to the server to be authenticated thus providing the eavesdropper with opportunity to steal valuable data. This paper presents a simple protocol based on zero knowledge proof by which the user can prove to the authentication server that he has the password without having to send the password to ...
openaire   +1 more source

Lightweight and Physically Secure Anonymous Mutual Authentication Protocol for Real-Time Data Access in Industrial Wireless Sensor Networks

IEEE Transactions on Industrial Informatics, 2019
Industrial wireless sensor network (IWSN) is an emerging class of a generalized WSN having constraints of energy consumption, coverage, connectivity, and security.
P. Gope, A. Das, Neeraj Kumar, Yongqiang Cheng   +3 more
semanticscholar   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source