Results 61 to 70 of about 224,651 (296)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Augmented Authenticity

open access: yesPrimitive Tider
As the name implies, augmented reality seeks to expand our experience of the real world - but it should also be considered a means of expanding a user's perception of their authentic physical surroundings.
Elisabeth Kjellin, Gunnar Liestøl
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Ewingella docleensis sp. nov. isolated from artisanal Montenegrin komanski cheese

open access: yesThe Microbe
Microorganisms play a dual role in the production of artisanal foods. On one hand, they contribute to the development of unique flavours, tastes and textures; on the other hand, certain microbes can pose risks, including spoilage or growth of foodborne ...
Beatriz Daza Prieto   +9 more
doaj   +1 more source

Dreaming of drams: Authenticity in Scottish whisky tourism as an expression of unresolved Habermasian rationalities [PDF]

open access: yes, 2011
In this paper, the production of whisky tourism at both independently owned and corporately owned distilleries in Scotland is explored by focusing on four examples (Arran, Glengoyne, Glenturret and Bruichladdich).
Spracklen, K, Karl Spracklen
core   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Authenticity and inauthenticity in narrative identity

open access: yesHeliyon, 2019
Self-reported authenticity is related to higher well-being, however, employing self-report questionnaires to measure authenticity may be limited in that they do not capture the lived experience of authenticity.
Joshua A. Wilt   +2 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

When Does Authenticity Benefit Employee Well-Being: A Relational Framework of Authenticity at Work

open access: yesAdministrative Sciences
Authenticity at work has emerged as a critical factor in employee well-being research, with extensive evidence supporting its positive organizational implications.
Di Xie, Ying Yang
doaj   +1 more source

Being Moved: Heideggerian Authenticity and Wolf's Nameless Virtue

open access: yes, 2022
Susan Wolf proposes that there is a virtue of character we all dimly recognize but cannot put a name to, a virtue that involves living with an expectation and a willingness to take responsibility for more than what one is rationally on the hook for.
Gray, David
core   +1 more source

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