Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
HUBUNGAN ANTARA AUTHORITATIVE PARENTING PRACTICES DENGAN PRESTASI BELAJAR PADA SISWA SMA DI BANDA ACEH [PDF]
Prestasi belajar merupakan salah satu tolak ukur dari keberhasilan siswa dalam dunia akademik yang dapat dipengaruhi oleh faktor internal dan faktor eksternal.
Zirlia Anggraini
core
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
THE RELATIONSHIP BETWEEN PARENTING STYLES AND PARENTAL FINANCIAL MONITORING [PDF]
Parenting styles are an important factor in how parents raise their children. This study investigated the relationship between parenting styles and parental financial monitoring.
Adam NDOU, Jethro GODI
doaj +1 more source
Fathers’ parenting styles in Chinese families in urban Malaysia [PDF]
The primary objectives of this study were to examine: 1) fathers’ parenting styles, and 2) the relationships between selected variables within the family ecosystems (e.g., father’s age, education, work hours, income, and psychological distress, child’s ...
Baharudin, Rozumah +2 more
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Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund +3 more
wiley +1 more source
Explanatory theoretical Model for Parenting Styles, Attachment Styles and Differentiation of couples [PDF]
parenting style can be a predictor of early maladaptive schemas and marital satisfaction. Understanding variables that effect of parenting style is very important.
azad gorbani, ahmad amani
doaj +1 more source
Role of parenting style and parents’ education in positive youth development of adolescents [PDF]
The main purpose of this research is to determine the role of parenting style and educational level of parents in Positive Youth Development (PYD). Data were obtained using a questionnaire method involving 496 adolescent students of national secondary ...
Hamsan, Hanina Halimatusaadiah +3 more
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Adult‐Onset Subacute Sclerosing Panencephalitis Presenting With Subacute Cognitive Deficits
ABSTRACT We describe the case of a 41‐year‐old man diagnosed with adult‐onset subacute sclerosing panencephalitis (SSPE). The patient presented with subacute progressive cognitive deficits and a neuropsychological profile indicating predominant frontoparietal dysfunction. MRI showed only mild parietal‐predominant cerebral atrophy.
Dennis Yeow +4 more
wiley +1 more source
Parenting styles and academic achievement [PDF]
Type of parenting style found to be influences the child's academic achievement. This study aimed to identify the type of parenting styles practiced by parents and its relationship to the academic achievement of children.They are 406 of form five ...
Hanafi, Zahyah +2 more
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