Results 181 to 190 of about 8,398,692 (261)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Prognostic role of triglyceride-glucose index and triglyceride-glucose body mass index in patients undergoing coronary artery bypass grafting: a systematic review and meta-analysis. [PDF]

J Thorac Dis
Chen D, Wei X, Sun H, Meng J, Huang Y, Lu X, Gao Y, Xu Z, Ma Y.   +8 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

From protocol angiography to selective coronary evaluation in sepsis-associated myocardial injury. [PDF]

Crit Care
Zhou X, Hua Z.
europepmc   +1 more source

Authors Index

The International Journal of Biological Markers, 1990
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

The LoVe score: Development and validation of a bedside clinical index to identify patients at risk for prolonged invasive mechanical ventilation. [PDF]

J Intensive Care Soc
Hilders PA, Lijović L, Otten M, Biesheuvel LA, Jagesar AR, Sigling O, Elbers PWG.   +6 more
europepmc   +1 more source

Authors Index

The International Journal of Biological Markers, 1996
doaj   +1 more source