Results 91 to 100 of about 827,442 (390)

Regression, developmental trajectory and associated problems in disorders in the autism spectrum: the SNAP study [PDF]

, 2008
We report rates of regression and associated findings in a population derived group of 255 children aged 9-14 years, participating in a prevalence study of autism spectrum disorders (ASD); 53 with narrowly defined autism, 105 with broader ASD and 97 with
A. LeCouteur, American Psychiatric Association, Andrew Pickles, B. M. Prizant, B. Taylor, C. A. Molloy, C. Lord, C. Lord, C. Lord, C. R. Marshall, D. Wechsler, David Meldrum, Devanitha Serkana, E. Fombonne, E. Werner, E. Werner, Emily Simonoff, F. DeStefano, F. R. Volkmar, G. Baird, G. Losche, Gillian Baird, H. Honda, H. Kurita, Iris Carcani-Rathwell, J Richler, J. C. Raven, J. C. Raven, J. L. Adrien, J. Osterling, L. G. Evans-Jones, L. Wing, M. Davidovitch, M. Valicenti-McDermott, P. A. Filipek, R. A. Carper, R. F. Tuchman, R. J. Landa, R. Kobayashi, R. Landa, R. Luyster, R. O. Robinson, S Sparrow, S. Chakrabarti, S. J. Rogers, S. Malhotra, S. O. Dahlgren, S. Ozonoff, S. Shinnar, Susie Chandler, Tom Loucas, Tony Charman, Y. Hoshino   +52 more
core   +2 more sources

The Autism‐Spectrum Quotient in siblings of people with Autism [PDF]

Autism Research, 2016
This study measures the distribution of autistic traits, using the autism‐spectrum quotient (AQ), in siblings of individuals with autism spectrum conditions (ASC). Total AQ scores, along with AQ subscales, were collected from child, adolescent and adult controls, siblings, and volunteers with ASC using one of the three age‐appropriate versions of the ...
Ruzich, Emily, Allison, Carrie, Smith, Paula, Ring, Howard, Auyeung, Bonnie, Baron-Cohen, Simon   +5 more
openaire   +6 more sources

Does Language Matter? Identity-First Versus Person-First Language Use in Autism Research: A Response to Vivanti

Journal of Autism and Developmental Disorders, 2020
In response to Vivanti’s ‘Ask The Editor…’ paper [ Journal of Autism and Developmental Disorders, 50 (2), 691–693], we argue that the use of language in autism research has material consequences for autistic people including stigmatisation ...
M. Botha, Jacqueline Hanlon, G. Williams
semanticscholar   +1 more source

Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1

Advanced Science, EarlyView.
The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo, Yuanyuan Li, Wensheng Li, Tongrui Wu, Yi Liu, Yacoubou Abdoul Razak Mahaman, Jianzhi Wang, Rong Liu, Wei Liu, Hui Shen, Xiaochuan Wang   +10 more
wiley   +1 more source

Delineation of the genetic and clinical spectrum of Phelan-McDermid syndrome caused by SHANK3 point mutations

Molecular Autism, 2018
Background Phelan-McDermid syndrome (PMS) is a neurodevelopmental disorder characterized by psychiatric and neurological features. Most reported cases are caused by 22q13.3 deletions, leading to SHANK3 haploinsufficiency, but also usually encompassing ...
Silvia De Rubeis, Paige M. Siper, Allison Durkin, Jordana Weissman, François Muratet, Danielle Halpern, Maria del Pilar Trelles, Yitzchak Frank, Reymundo Lozano, A. Ting Wang, J. Lloyd Holder, Catalina Betancur, Joseph D. Buxbaum, Alexander Kolevzon   +13 more
doaj   +1 more source

Change detection in children with autism: an auditory event-related fMRI study [PDF]

, 2006
Autism involves impairments in communication and social interaction, as well as high levels of repetitive, stereotypic and ritualistic behaviours, and extreme resistance to change. This latter dimension, whilst required for a diagnosis, has received less
Ashwin, C, Baron-Cohen, S, Belmonte, MK, Bernard, FA, Bullmore, ET, Davis, MH, Gomot, M   +6 more
core   +1 more source

The Diagnosis of Autism: From Kanner to DSM-III to DSM-5 and Beyond

Journal of Autism and Developmental Disorders, 2021
In this paper we review the impact of DSM-III and its successors on the field of autism—both in terms of clinical work and research. We summarize the events leading up to the inclusion of autism as a “new” official diagnostic category in DSM-III, the ...
Nicole E. Rosen, C. Lord, F. Volkmar
semanticscholar   +1 more source

Parvalbumin Interneuron‐Dependent Hippocampal Neurogenesis Evoked by Prolonged Rhythmic Light Flicker

Advanced Science, EarlyView.
This study demonstrates that prolonged rhythmic 40 Hz light flicker enhances spatial learning by stimulating PV interneuron‐dependent neurogenesis. The light flicker selectively activates PV interneurons, which enhances GABAergic support for the integration of immature neurons in the adult dentate gyrus.
Hai Yan, Yunxuan Wang, Xufan Deng, Shiyu Wu, Yifan Pan, Jun Du, Mei Yu, Bo Liu, Huimei Wang, Zhengyu Zhang, Jinghong Chen, Shuifa Chen, Yizheng Wang, Tara Walker, Perry Bartlett, Jun Ju, Sheng‐Tao Hou   +16 more
wiley   +1 more source

Multi‐Region Brain Organoids Integrating Cerebral, Mid‐Hindbrain, and Endothelial Systems

Advanced Science, EarlyView.
Multi‐Region Brain Organoids combine cerebral, mid/hindbrain, and endothelial components into an advanced 3D model capturing 80% of fetal brain cellular diversity. This platform reveals essential endothelial‐neural signaling networks that maintain region‐specific intermediate progenitors during hindbrain development.
Anannya Kshirsagar, Hayk Mnatsakanyan, Sai Kulkarni, John Guo, Kai Cheng, Luke Daniel Ofria, Oce Bohra, Ram Sagar, Vasiliki Mahairaki, Christian E Badr, Annie Kathuria   +10 more
wiley   +1 more source

Autistic adults have poorer quality healthcare and worse health based on self-report data

Molecular Autism, 2022
Background Recent research suggests that autistic individuals have shorter lifespans and experience worse health (greater health burden) than non-autistic individuals.
Elizabeth Weir, Carrie Allison, Simon Baron-Cohen   +2 more
doaj   +1 more source