Results 41 to 50 of about 674,158 (360)

The prevalence and incidence of mental ill-health in adults with autism and intellectual disabilities [PDF]

, 2008
The prevalence, and incidence, of mental ill-health in adults with intellectual disabilities and autism were compared with the whole population with intellectual disabilities, and with controls, matched individually for age, gender, ability-level, and ...
A. V. Brereton, Alison Jackson, B. Holden, C. Lord, C. Morgan, C. W. McGrother, Craig A. Melville, D. G. Allen, D. Mantry, Dipali Mantry, E. A. Bradley, E. A. Bradley, E. Billstedt, E. Smiley, E. Tsakanikos, E. Tsakanikos, Elita Smiley, F. Tyrer, G. Baird, G. Dawson, H. Leonard, H. Schrojenstein Lantman-de Valk van, H. W. M. Kwok, J. Bertrand, J. Hill, J. K. Kern, J. L. Matson, J. L. Matson, J. Robertson, Janet Finlayson, Jill Morrison, K. McClintock, L. Lecavalier, L. Wing, Linda Allan, M Yeargin-Allsopp, M. E. Stewart, M. G. Aman, M. Ghaziuddin, M. Ghaziuddin, M. Hotopf, M. M. Konstantareas, M. Wullink, N. Holmes, National Initiative: Autism Screening, Assessment, P. A. Filipek, P. Sturmey, P. W. Davidson, R. A. Collacott, R. Didden, R. Didden, R. Farmer, R. M. Reese, S. -A. Cooper, S. -A. Cooper, S. A. Borthwick-Duffy, S. A. Cooper, S. A. Cooper, S. Bhaumik, S. Chakrabarti, S. Chakrabarti, S. Deb, S. Moss, Sally-Ann Cooper, Scottish Intercollegiate Guideline Network, T. D. Cook, World Health Organisation, World Health Organisation   +67 more
core   +1 more source

Elevated fetal steroidogenic activity in autism [PDF]

, 2014
Autism affects males more than females, giving rise to the idea that the influence of steroid hormones on early fetal brain development may be one important early biological risk factor.
Abdallah, M W, Auyeung, B, Baron-Cohen, S, Chakrabarti, B, Cohen, A S, Hougaard, D M, Lombardo, M V, Melgaard, L, Nørgaard-Pedersen, B, Ruta, L   +9 more
core   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei, Elena Parrini, Claudia Bianchini, Maria Luisa Ricci, Renzo Guerrini   +4 more
wiley   +1 more source

PeakCaller: an automated graphical interface for the quantification of intracellular calcium obtained by high-content screening

BMC Neuroscience, 2017
Background Intracellular calcium is an important ion involved in the regulation and modulation of many neuronal functions. From regulating cell cycle and proliferation to initiating signaling cascades and regulating presynaptic neurotransmitter release ...
Elena Artimovich, Russell K. Jackson, Michaela B. C. Kilander, Yu-Chih Lin, Michael W. Nestor   +4 more
doaj   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Augmentative and alternative communication for children with autism spectrum disorder: An evidence-based evaluation of the Language Acquisition through Motor Planning (LAMP) programme

Cogent Education, 2015
Children diagnosed with autism spectrum disorder often have restricted verbal communication. For children who do not use functional speech, augmentative and alternative communication (AAC) devices can be an important support.
Mary-Ann Naguib Bedwani, Susan Bruck, Debra Costley   +2 more
doaj   +1 more source

A Qualitative Study of the Effects of the University of Arkansas Autism Support Program [PDF]

, 2017
Individuals who have been diagnosed with autism spectrum disorder are often united by the following characteristics: difficulty communicating and interacting with others, inhibited ability to function socially, difficulty functioning academically or at ...
Post, Jessica
core   +2 more sources

Prenatal Neurogenesis in Autism Spectrum Disorders. [PDF]

, 2016
An ever-increasing body of literature describes compelling evidence that a subset of young children on the autism spectrum show abnormal cerebral growth trajectories.
Kaushik, Gaurav, Zarbalis, Konstantinos S   +1 more
core   +1 more source

Characteristics of Cerebral Palsy in the Midwestern US

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim, Kelsey Steffen, Lauren Gottschalk‐Henneberry, Jennifer Miros, Amy Robichaux‐Viehoever, Karen Taca, Bhooma R. Aravamuthan   +6 more
wiley   +1 more source

Pharmacological treatment in autism: a proposal for guidelines on common co-occurring psychiatric symptoms

BMC Medicine
Background The prevalence of autism spectrum disorder (ASD) has surged, with an estimated 1 in 36 eight-year-olds in the United States meeting criteria for ASD in 2020.
Mariah A. Manter, Kirstin B. Birtwell, James Bath, Nora D. B. Friedman, Christopher J. Keary, Ann M. Neumeyer, Michelle L. Palumbo, Robyn P. Thom, Emily Stonestreet, Hannah Brooks, Kelly Dakin, Jacob M. Hooker, Christopher J. McDougle   +12 more
doaj   +1 more source