Results 61 to 70 of about 361,059 (344)
Parabiosis, Assembloids, Organoids (PAO)
Advanced Science, EarlyView.This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong +5 more
wiley +1 more source
Sleep Problems in Children With Autism Spectrum Disorder [PDF]
, 2020 The purpose of the current study was to examine the effect of restricted and repetitive behaviors (RRBs) on the relationship between sleep problems and externalizing behaviors in young children with autism spectrum disorder (ASD).
Alba, Laura A
core
Attentional allocation of autism spectrum disorder individuals: Searching for a Face-in-the-Crowd. [PDF]
, 2015 A study is reported which tests the proposition that faces capture the attention of those with autism spectrum disorders less than a typical population.
Heavey, L, Moore, DJ, Reidy, J
core +1 more source
Genetic landscape of autism spectrum disorder in Vietnamese children [PDF]
, 2020 Autism spectrum disorder (ASD) is a complex disorder with an unclear aetiology and an estimated global prevalence of 1%. However, studies of ASD in the Vietnamese population are limited.
Bui, HTP +12 more
core +2 more sources
Recognizing autism spectrum disorder
JAAPA, 2019 ABSTRACT Autism spectrum disorder (ASD), previously called autism, is a developmental condition that can cause significant social, communication, and behavioral challenges. Early symptoms of ASD can easily be overlooked. Clinicians who can recognize the symptoms of ASD can help children get prompt referral to specialists and early ...
Theresa, Bartolotta, Denise, Rizzolo
openaire +3 more sources
Advanced Science, EarlyView.Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu +14 more
wiley +1 more source
Advanced Science, EarlyView.This study describes derivation of two distinct mechanosensory subpopulations from human pluripotent stem cells using a transcription factor mediated approach. Of significance, functional interrogation of induced mechanosensory subtypes reveal their unique responses to mechanical stimulation in the absence of end‐organs.
Amy J. Hulme +12 more
wiley +1 more source
Autism spectrum disorder: A mitochondrial disorder.
Iranian journal of child neurology, 2021 none ...
openaire +2 more sources
Advanced Science, EarlyView.Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi +5 more
wiley +1 more source
The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia
Advanced Science, EarlyView.The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo +3 more
wiley +1 more source