Results 51 to 60 of about 2,929,561 (349)

Autistic Disorder in Patients with Williams-Beuren Syndrome: A Reconsideration of the Williams-Beuren Syndrome Phenotype

PLoS ONE, 2012
Background Williams-Beuren syndrome (WBS), a rare developmental disorder caused by deletion of contiguous genes at 7q11.23, has been characterized by strengths in socialization (overfriendliness) and communication (excessive talkativeness).
S. Tordjman, G. Anderson, M. Botbol, A. Toutain, P. Sarda, M. Carlier, P. Saugier-Veber, C. Baumann, D. Cohen, C. Lagneaux, A. Tabet, A. Verloes   +11 more
semanticscholar   +1 more source

Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1

Advanced Science, EarlyView.
The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo, Yuanyuan Li, Wensheng Li, Tongrui Wu, Yi Liu, Yacoubou Abdoul Razak Mahaman, Jianzhi Wang, Rong Liu, Wei Liu, Hui Shen, Xiaochuan Wang   +10 more
wiley   +1 more source

The impact of schizotypy on quality of life among adults with autism spectrum disorder

BMC Psychiatry, 2022
Background Autism spectrum disorder (ASD) and schizotypal personality disorder can be difficult to distinguish. Deficits in social relationships and social interaction, present in both conditions, are known to impair quality of life.
Albin Klang, Britta Westerberg, Mats B. Humble, Susanne Bejerot   +3 more
doaj   +1 more source

Parvalbumin Interneuron‐Dependent Hippocampal Neurogenesis Evoked by Prolonged Rhythmic Light Flicker

Advanced Science, EarlyView.
This study demonstrates that prolonged rhythmic 40 Hz light flicker enhances spatial learning by stimulating PV interneuron‐dependent neurogenesis. The light flicker selectively activates PV interneurons, which enhances GABAergic support for the integration of immature neurons in the adult dentate gyrus.
Hai Yan, Yunxuan Wang, Xufan Deng, Shiyu Wu, Yifan Pan, Jun Du, Mei Yu, Bo Liu, Huimei Wang, Zhengyu Zhang, Jinghong Chen, Shuifa Chen, Yizheng Wang, Tara Walker, Perry Bartlett, Jun Ju, Sheng‐Tao Hou   +16 more
wiley   +1 more source

Gastrodin Rescues Autistic-Like Phenotypes in Valproic Acid-Induced Animal Model

Frontiers in Neurology, 2018
Autism spectrum disorder (ASD) is an immensely challenging developmental disorder characterized by impaired social interaction, restricted/repetitive behavior, and anxiety.
Xiaona Wang, Jing Tao, Yidan Qiao, Shuying Luo, Zhenqin Zhao, Yinbo Gao, Jisheng Guo, Jinghui Kong, Chongfen Chen, Lili Ge, Bo Zhang, Pengbo Guo, Lei Liu, Yinsen Song   +13 more
doaj   +1 more source

Autism Spectrum Disorder and International Travel [PDF]

International Journal of Travel Medicine and Global Health, 2018
The literature on international travellers with psychiatric disorders is limited. This perspective article highlights various travel-related aspects of autism spectrum disorder (ASD), including its aetiological association with maternal migration, the ...
Wee Xuan Neo, Gerard Flaherty
doaj   +1 more source

Language in Low-Functioning Children with Autistic Disorder: Differences Between Receptive and Expressive Skills and Concurrent Predictors of Language

Journal of Autism and Developmental Disorders, 2012
Language profiles of children with autistic disorder and intellectual disability (n = 36) were significantly different from the comparison groups of children with intellectual disability (n = 26) and typically developing children (n = 34).
Jarymke Maljaars, I. Noens, E. Scholte, I. Berckelaer-Onnes   +3 more
semanticscholar   +1 more source

Multi‐Region Brain Organoids Integrating Cerebral, Mid‐Hindbrain, and Endothelial Systems

Advanced Science, EarlyView.
Multi‐Region Brain Organoids combine cerebral, mid/hindbrain, and endothelial components into an advanced 3D model capturing 80% of fetal brain cellular diversity. This platform reveals essential endothelial‐neural signaling networks that maintain region‐specific intermediate progenitors during hindbrain development.
Anannya Kshirsagar, Hayk Mnatsakanyan, Sai Kulkarni, John Guo, Kai Cheng, Luke Daniel Ofria, Oce Bohra, Ram Sagar, Vasiliki Mahairaki, Christian E Badr, Annie Kathuria   +10 more
wiley   +1 more source

A Comparison of Autistic Like Traits in the Relatives of Patients with Autism and Schizophrenia Spectrum Disorder

Iranian Journal of Psychiatry, 2018
Objective: This study aimed to identify autistic like traits in relatives of patients with schizophrenia and autism spectrum disorder. Method: causal-comparative research design was utilized.
Zeynab Khanjani, Shahin Azmoodeh, Majid Mahmoudaliloo, Gholamreza Noorazar   +3 more
doaj  

“Work WITH us”: a Delphi study about improving eating disorder treatment for autistic women with anorexia nervosa

Journal of Eating Disorders, 2023
Plain English summary Autistic women are more likely to have anorexia nervosa (AN) than non-autistic women. Autistic women can find eating disorder treatment unhelpful and need adaptations to treatment.
Sarah L. Field, John R. E. Fox, Catherine R. G. Jones, Marc O. Williams   +3 more
doaj   +1 more source