Results 51 to 60 of about 105,746 (303)

A Brain‐Wide Atlas of Astrocytic Oxytocin Receptors Reveals a Glial Basis for Nucleus Accumbens Modulation of Affiliative Behavior

Advanced Science, EarlyView.
The cellular actors of oxytocin signaling are under intense scrutiny. A brain‐wide anatomical and functional analysis in mice and rats reveals widespread expression of oxytocin receptors in astrocytes. These receptors are functionally active and, in the nucleus accumbens, selectively regulate male social affiliation.
Clémence Denis, Stefan Stojilkovic, Kai‐Yi Wang, Cristina Márquez, Annabel C. Kleinwächter, Angel Baudon, Yuval Podpecan, Aurélia Ces, Mélanie Kremer, Isabelle Arnoux, Nathalie Rouach, Jemima Helen, Sophie Trender, Andreas Wallkum, Selina Wunsch, Franziska Schommer, Moritz C. Wimmer, Tim Schubert, Felix Franke, Jabir Aliyu Muhammad, Eva M. Eisemann, Ingrid Camila Possa‐Paranhos, Cassandra Baumann, Pierre‐Alexis Derrien, Quirin Krabichler, Cosmo Garcia, Henning Fröhlich, Matthew K. Kirchner, Valery Grinevich, Pascal Darbon, Javier E. Stern, Ferdinand Althammer, Alexandre Charlet   +32 more
wiley   +1 more source

Sense of presence and atypical social judgments in immersive virtual reality: responses of adolescents with Autistic Spectrum Disorders

, 2010
Immersive virtual environments (IVEs) are potentially powerful educational resources but their application for children with autistic spectrum disorder (ASD) is under researched. This study aimed to answer two research questions: (1) do children with ASD
White, K., Bailey, A, Wallace, S., White, K, Westbury, A, Parsons, Sarah, Westbury, A., Bailey, A., Wallace, S, Parsons, S.   +9 more
core   +1 more source

Prior Expectations Bias Confidence Judgments Through Parietal Alpha‐Band Modulation

Advanced Science, EarlyView.
ABSTRACT Humans possess the metacognitive ability to estimate the likely accuracy of their own decisions through confidence judgments. Yet, whether prior information shapes confidence and the neural mechanisms mediating such influence, remain to be determined.
Luca Tarasi, Anna Pasini, Domenico Romanazzi, Margherita Covelli, Vincenzo Romei   +4 more
wiley   +1 more source

Autistic spectrum disorders and primary-secondary transition [PDF]

, 2006
Transition from primary to secondary school has been a focus of concern regarding pupil anxiety, social integration, lack of progression and underachievement, particularly for children/young people with special educational needs (SEN).
Jindal-Snape, D.; id_orcid, Topping, K. J.; id_orcid, Kerr, C., Douglas, W., Smith, E. F.   +4 more
core  

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

ANKS1B in the Nucleus Accumbens Controls Escalated Cocaine Self‐Administration via Regulating CBP‐FoxO3 Complex

Advanced Science, EarlyView.
ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang, Xiaoxuan Wu, Xuan Chen, Chao Peng, Zihang Li, Shumin Gao, Shiqiu Meng, Jing Dong, Dong Wu, Liying Lv, Ying Han, Yanxue Xue, Lin Lu, Jie Shi, Jianfeng Liu, Yan Sun   +15 more
wiley   +1 more source

Association of self-harm and suicidality with psychiatric co-occurring conditions in autistic individuals: a systematic review and pooled analysisResearch in context

EClinicalMedicine
Summary: Background: Autistic individuals frequently experience psychiatric co-occurring conditions, but the association with self-harm/suicidality according to these conditions was not yet elucidated.
Jae Han Kim, Juhyun Lee, Songjoo Shim, Keun-Ah Cheon   +3 more
doaj   +1 more source

Deficits in facial, body movement and vocal emotional processing in autism spectrum disorders [PDF]

, 2010
Background. Previous behavioural and neuroimaging studies of emotion processing in autistic spectrum disorder (ASD) have focused on the use of facial stimuli. To date, however, no studies have examined emotion processing in autism across a broad range of
Santos, I. M., Calder, A. J., Sprengelmeyer, R, Atkinson, A P, Whalley, H. C., Young, A W, Johnstone, E.C., Santos, I.M., Young, A.W., Lawrie, S.M., Lawrie, S M, Hall, J., Sprengelmeyer, R., Stanfield, A.C., Johnstone, E C, Santos, I M, Whalley, H.C, Philip, R. C. M., Calder, A J, Young, A. W., Stanfield, A C, Johnstone, E. C., Lawrie, S. M., Atkinson, A. P., Sprengelmeyer, Reiner Heinrich, Whalley, Heather, Philip, R C M, Hall, J, Hall, Jeremy, Calder, A.J., Stanfield, A. C., Atkinson, A.P., Philip, R.C.M.   +32 more
core   +1 more source

Gasdermin D‐Mediated Release of IL‐33 Results in Fetal Brain Developmental Abnormalities During Maternal Colitis

Advanced Science, EarlyView.
Under colitis, Gsdmd mediates the release of IL‐33 from the epithelium of pregnant mice. IL‐33 can cross the placenta and enhance the proliferative capacity of neural stem cells, ultimately resulting in behavioral deficits in the offspring. Excessive pyroptosis in the colonic epithelium also triggers the translocation of LPS, which in turn increases ...
Huiyang Jia, Shukui Zhang, Kai Ma, Jie Zhou, Jianwei Jiao   +4 more
wiley   +1 more source

A Comparison of Autistic Like Traits in the Relatives of Patients with Autism and Schizophrenia Spectrum Disorder

Iranian Journal of Psychiatry, 2018
Objective: This study aimed to identify autistic like traits in relatives of patients with schizophrenia and autism spectrum disorder. Method: causal-comparative research design was utilized.
Zeynab Khanjani, Shahin Azmoodeh, Majid Mahmoudaliloo, Gholamreza Noorazar   +3 more
doaj