Results 201 to 210 of about 518,494 (282)

Development of three-colour FRET cascade for force sensing of the putative RIAM-vinculin interaction in fibroblasts. [PDF]

Commun Chem
Treacy CA, Pallett TL, Bui TTT, Poland SP, Pfuhl MA, Parsons M, Ameer-Beg SM.   +6 more
europepmc   +1 more source

Frontiers of Bright CEP‐Stable Broadband Infrared Sources

Laser &Photonics Reviews, EarlyView.
Bright CEP‐stable broadband infrared sources push the limits of ultrafast science by delivering exceptional brightness alongside few‐cycle durations and multi‐octave spectral coverage. This review highlights emerging architectures and nonlinear conversion strategies that scale power while preserving phase stability.
Ugaitz Elu, Jens Biegert
wiley   +1 more source

Beyond a gatekeeper: the non-classical signaling role of STRA6 in driving endothelial senescence and atherosclerosis. [PDF]

Front Immunol
Yuan Y, Wang J, Zhang Y, Yu Y, Shi W, Chen S, Kuang Y, Feng L.   +7 more
europepmc   +1 more source

Osteoarthritis: An Immuno‐Inflammatory Disease‐Mechanisms of Immune Cell Dysregulation and Potential Therapeutic Strategies

Med Research, EarlyView.
This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei, Xiaoxian Lou, Xu Su, Shubao Liu, Yanli Tong, Jie Chen, Xuerui Chen, Wenjun Mao, Hui Yu, Liangbin Lin   +9 more
wiley   +1 more source

The toxin–antitoxin complex Fic‐1–AntF functions as a deAMPylase that regulates the activity of DNA gyrase

mLife, EarlyView.
Abstract Toxin–antitoxin (TA) systems found in diverse bacteria play important roles in their adaptation to changing environments. The toxin of the Fic‐1–AntF TA pair from Pseudomonas bijieensis strain 2P24 inhibits bacterial DNA replication by attacking the subunit B of DNA gyrase (GyrB) via AMPylation, while the antitoxin AntF blocks its enzymatic ...
Furong Chen, Liwei Guo, Canhua Lu, Wenjun Jiang, Zhao‐Qing Luo, Junfeng Liu, Li‐Qun Zhang   +6 more
wiley   +1 more source

Diabetic neuropathy's immune-metabolic network: mechanistic complexity, therapeutic challenges, and the path forward. [PDF]

Front Immunol
Sun W, Yang K, Song Y.
europepmc   +1 more source

Muscle‐Specific Kinase Signaling and Its Therapeutic Potential

Muscle &Nerve, EarlyView.
ABSTRACT The function of the neuromuscular junction (NMJ) is compromised in many neuromuscular diseases (NMDs) such as autoimmune or congenital myasthenia gravis (MG), amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA), and muscular dystrophies.
Stine Marie Jensen, Dana L. E. Vergoossen, Maartje G. Huijbers   +2 more
wiley   +1 more source

The Regulation and Function of Hippo/YAP Pathway in Cancer. [PDF]

FASEB J
Ghosh C, Kakar R, Torkamboor S, Sun Y.
europepmc   +1 more source

Theory and Experimental Study of Two-stage Auto-cascade Low Temperature Refrigerator

Journal of Mechanical Engineering, 2014
openaire   +1 more source

When wolves aren't enough: revisiting trophic cascades in northern Wisconsin

Oikos, EarlyView.
Elimination of top predators has allowed large herbivores to flourish in many terrestrial ecosystems, transforming food webs and ecosystem functions. Restoration of large predator communities is hoped to reverse negative effects of this trophic downgrading, but evidence for such effects is elusive.
Elaine M. Brice, Donald M. Waller, Jennifer L. Price Tack, Daniel J. Storm, David A. Rogers, Sarah E. Johnson, Bernd Blossey   +6 more
wiley   +1 more source