Results 211 to 220 of about 710,516 (276)

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

iNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin, Xianfeng Yu, Yayu Wang, Xiaohan Song, Yuehua Wang, Zhixin Wang, Wei Miao, Xudong Yang, Jiajia Zhu, Xiaoqun Zhu, Maria‐Trinidad Herrero   +10 more
wiley   +1 more source

Efficient production of fully active, SARS-CoV-2-priming, wildtype TMPRSS2 ectodomain via co-expression of HAI-2 allows for both auto- and cross-activation mechanisms. [PDF]

Biochem J
Végh B, Kocsis A, Dobó J, Balczer J, Kiss B, Pál G, Gál P.   +6 more
europepmc   +1 more source

Exposure–Recovery Approach for Hepatic Toxicity Analysis of Pyrethroid Lambda‐Cyhalothrin: Histopathological, Histochemical, and Biochemical Responses in Oreochromis niloticus

Journal of Applied Toxicology, EarlyView.
ABSTRACT Lambda‐cyhalothrin is a synthetic pyrethroid insecticide widely used in agriculture, but its potential to contaminate aquatic ecosystems and exert high toxicity on fish at low concentrations raises ecotoxicological concerns. While standard histopathological and biochemical assessments are common, the novel integration of pigment‐based ...
Carlos Eurico Fernandes, André Luiz do Nascimento Silva, Tiago Venancio da Silva, Karine Nathiele Nogueira Farias, Sabrina Fuzer Gonçalves, Brenda de Oliveira Martins, Maria Eduarda Corona Garcia, Lilian Franco‐Belussi   +7 more
wiley   +1 more source

Complement-related genetic analysis for Japanese children with transplant-associated thrombotic microangiopathy. [PDF]

Front Pediatr
Yamada A, Nagasawa S, Nakagawa M, Kamimura S, Sakata N, Nakayama H, Hasegawa D, Okamoto Y, Takeuchi M, Ohara O, Moritake H.   +10 more
europepmc   +1 more source

Deep Learning and Machine Learning Algorithms for Cervical Cancer Segmentation on MRI: A Systematic Review

Journal of Medical Radiation Sciences, EarlyView.
This systematic review summarizes current evidence on machine and deep learning algorithms for MRI‐based cervical cancer segmentation, demonstrating promising diagnostic performance and potential for workflow automation. However, methodological heterogeneity, limited external validation, and low certainty of evidence highlight the need for standardized
Somayeh Haji Ahmadi, Sina Soltan Mohammadi, Abolfazl Koozari, Mohammadreza Elhaie   +3 more
wiley   +1 more source

Knowledge Distillation in Object Detection: A Survey from CNN to Transformer. [PDF]

Sensors (Basel)
Shehzadi T, Noor R, Ifza I, Liwicki M, Stricker D, Afzal MZ.   +5 more
europepmc   +1 more source

NTECARS: A Nonthermal Equilibrium CARS Spectra Fitting Code

Journal of Raman Spectroscopy, EarlyView.
We present NTECARS, an open‐source code written in Julia for the calculation and fitting of CARS spectra under nonequilibrium conditions. Rovibrational distributions can be flexibly modeled and fitted for different use cases. The code currently implements CO2$$ \mathrm{C}{\mathrm{O}}_2 $$ and N2$$ {\mathrm{N}}_2 $$ molecules and is validated under ...
Christian A. Busch, Uwe Czarnetzki
wiley   +1 more source

Spatiotemporal analysis of genetic perturbations reveals a genetic cascade driving Tribolium gap gene initialization. [PDF]

Biol Open
Ahmadi M, Rudolf H, Mau C, Garcia-Guillen J, El-Sherif E.   +4 more
europepmc   +1 more source

Influence of the growing area on cone yield and alpha and beta acid content in Cascade hops: An Italian case study

JSFA reports, EarlyView.
Abstract Background Territorial food production is a well‐known quality trait, which is attracting new customer preferences for different agricultural products. In this context, many microbreweries and agricultural breweries started to cultivate their own small hopyard to exploit the so‐called “terroir” effect.
Paolo Loreti, Roberto Ruggeri, Angelo Rossini, Luca Saltalamacchia, Francesco Rossini   +4 more
wiley   +1 more source

The forgotten billion: bridging the global allergy care chasm through scalable, equity-driven strategies. [PDF]

Front Allergy
Li SG, Zhang L, Zhang J, Li J, Zou Y, Long T, Yu R, Zhang Y.   +7 more
europepmc   +1 more source