Results 21 to 30 of about 710,516 (276)

Phospho-regulation of the Neurospora crassa septation initiation network. [PDF]

open access: yesPLoS ONE, 2013
Proper cell division is essential for growth and development of uni- and multicellular organisms. The fungal septation initiation network (SIN) functions as kinase cascade that connects cell cycle progression with the initiation of cytokinesis.
Yvonne Heilig   +2 more
doaj   +1 more source

The study of thermodynamic properties of zeotropic mixtures of R600a/R23/R14

open access: yesAdvances in Mechanical Engineering, 2017
Thermodynamic properties of zeotropic mixtures of R600a/R23/R14 have been investigated and calculated based on the established mathematical model. The deviations of bubble pressure and vapor composition between the simulation results and the experimental
Yinlong Wu   +4 more
doaj   +1 more source

Automatic Malignant Thyroid Nodule Recognition in Ultrasound Images based on Deep Learning [PDF]

open access: yesE3S Web of Conferences, 2020
As the most common malignancy in the endocrine system, thyroid cancer is usually diagnosed by discriminating the malignant nodules from the benign ones using ultrasonography, whose interpretation results primarily depends on the subjectivity judgement of
Zhou Meng   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

FMRP deficiency leads to multifactorial dysregulation of splicing and mislocalization of MBNL1 to the cytoplasm.

open access: yesPLoS Biology, 2023
Fragile X syndrome (FXS) is a neurodevelopmental disorder that is often modeled in Fmr1 knockout mice where the RNA-binding protein FMRP is absent. Here, we show that in Fmr1-deficient mice, RNA mis-splicing occurs in several brain regions and peripheral
Suna Jung   +3 more
doaj   +1 more source

State Feedback Speed Control with Periodic Disturbances Attenuation for PMSM Drive

open access: yesEnergies, 2022
This paper proposes an auto-tuned constrained state-feedback controller (SFC) to attenuate periodic disturbances present in permanent magnet synchronous (PMSM) motor drives.
Łukasz J. Niewiara   +3 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Critical evaluation of kinetic schemes for coagulation.

open access: yesPLoS ONE, 2023
Two well-established numerical representations of the coagulation cascade either initiated by the intrinsic system (Chatterjee et al., PLOS Computational Biology 2010) or the extrinsic system (Butenas et al., Journal of Biological Chemistry, 2004) were ...
Alexandre Ranc   +5 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Wide dynamic range 500 fA sensitivity current measurement instrument

open access: yesMATEC Web of Conferences, 2017
Main technical features of Low Energy Charged Particle Sensor (LECPS) are described, taking into account LECPS high sensitivity, wide dynamic range, and conditions of in-flight operation on-board a satellite.
Pelemeshko Anatoly   +4 more
doaj   +1 more source

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