Results 111 to 120 of about 236,633 (242)

Ageing and Autoantibodies

Autoimmunity, 1988
Immune responsiveness decreases with age, while the production of autoantibodies increases, indicating that these are end results of perturbations in the regulatory mechanisms of the immune system. The effects of ageing on the immune system are reviewed.
Yaron Tomer, Yehuda Shoenfeld
openaire   +3 more sources

γδ T cells affect IL-4 production and B-cell tolerance [PDF]

, 2014
γδ T cells can influence specific antibody responses. Here, we report that mice deficient in individual γδ T-cell subsets have altered levels of serum antibodies, including all major subclasses, sometimes regardless of the presence of αβ T cells.
Andrew Getahun, Cohen, Finkelman, Gerber, Greg A. Kirchenbaum, Hidaka, Hirose, Hua Huang, Izui, John C. Cambier, Koichi Ikuta, Kubo, Lawrence J. Wysocki, M. Kemal Aydintug, Rebecca L. O’Brien, Ryan A. Heiser, Simon R. Carding, Sperling, Sunaga, Tamara L. Casper, Thiago O. Detanico, Willi K. Born, Yafei Huang   +22 more
core   +1 more source

Myocardial aging as a T-cell–mediated phenomenon [PDF]

, 2017
In recent years, the myocardium has been rediscovered under the lenses of immunology, and lymphocytes have been implicated in the pathogenesis of cardiomyopathies with different etiologies.
Abeßer, Marco, Beyersdorf, Niklas, Burkard, Matthias, Frantz, Stefan, Friedrich, Mike, Heinze, Katrin G., Hofmann, Ulrich, Jocelyne, Demengeot, Kerkau, Thomas, Nunes-Silva, Vânia, Peters, Laura, Pinnecker, Jürgen, Ramos, Gustavo Campos, Schuh, Kai, van den Berg, Anne, Weirather, Johannes   +15 more
core   +1 more source

Editorial: Autoantibodies [PDF]

Frontiers in Immunology, 2019
Holmdahl, Rikard, Nimmerjahn, Falk, Ludwig, Ralf J.   +2 more
openaire   +3 more sources

Studies on Autoantibodies in Human Sera [PDF]

, 1953
Alexander S. Wiener, Eve B. Gordon, Carol Gallop   +2 more
openalex   +1 more source

A novel platform for isotype-specific testing of autoantibodies.

PLoS ONE, 2019
The objective of this study was to test if a novel platform could be used for isotype-specific autoantibody testing in humans. Further, we evaluated if testing with this novel platform enables earlier detection of insulin autoantibodies in individuals ...
Kaylene L Carter, Anckia Treurnicht, Kara L Davis, Rajiv B Kumar, Brian J Feldman   +4 more
doaj   +1 more source

Parkinson's disease: autoimmunity and neuroinflammation [PDF]

, 2016
Parkinson's disease is a neurodegenerative disease that causes the death of dopaminergic neurons in the substantia nigra. The resulting dopamine deficiency in the basal ganglia leads to a movement disorder that is characterized by classical parkinsonian ...
CINIGLIO APPIANI, MARIO, CONTE, MICHELA, DE VINCENTIIS, Marco, DE VIRGILIO, ARMANDO, FABBRINI, Giovanni, GALLO, Andrea, GRECO, Antonio, INGHILLERI, Maurizio, RIZZO, MARIA IDA, ROSATO, CHIARA   +9 more
core   +1 more source

Dynamic disorganization of synaptic NMDA receptors triggered by autoantibodies from psychotic patients

Nature Communications, 2017
The identification of circulating autoantibodies against neuronal receptors in neuropsychiatric disorders has fostered new conceptual and clinical frameworks.
J. Jezequel, E. Johansson, J. Dupuis, V. Rogemond, H. Gréa, Blanka Kellermayer, N. Hamdani, Emmanuel Le Guen, C. Rabu, Marilyn Lepleux, Marianna Spatola, Elodie Mathias, Delphine Bouchet, A. Ramsey, R. Yolken, R. Tamouza, J. Dalmau, J. Honnorat, M. Leboyer, L. Groc   +19 more
semanticscholar   +1 more source

Serum Autoantibodies in Myasthenia Gravis and Thymoma: Selective Affinity for I-Bands of Striated Muscle As a Guide to Identification of Antigen(s) [PDF]

, 1967
Arthur J. L. Strauss, Pierson G. Kemp
openalex   +1 more source

Optimized purification strategies for the elimination of non-specific products in the isolation of GAD65-specific monoclonal autoantibodies [version 2; referees: 2 approved, 1 approved with reservations]

F1000Research, 2016
Autoantibodies against antigens expressed by insulin-producing β cells are circulating in both healthy individuals and patients at risk of developing Type 1 diabetes.
Wei Jiang, Henriette Macmillan, Anne-Marie Madec, Elizabeth D. Mellins   +3 more
doaj   +1 more source