Results 141 to 150 of about 151,970 (246)

Comparison of a novel micro-assay for insulin autoantibodies with the conventional radiobinding assay [PDF]

, 1998
Heike E. Naserke, Nicoletta Dozio, A G Ziegler, Ezio Bonifacio   +3 more
openalex   +1 more source

Lifelong evolution of autoreactive plasma cell numbers, affinity and anatomical location in arthritic K/BxN mice

Arthritis &Rheumatology, Accepted Article.
Objective The spontaneous K/BxN mouse model of rheumatoid arthritis has been used extensively to study chronic inflammation, contribution of immune cells, and the primordial role of autoreactive antibodies in disease initiation and severity. Only the ubiquitous enzyme glucose‐6‐phosphate isomerase (GPI) is the target of IgG autoantibodies secreted by ...
Thibault Vanhoucke, Carlos Castrillon, Odile Richard‐Le Goff, Angga Perima, Matteo Broketa, Andrew D. Griffiths, Patrick England, François Huetz, Pierre Bruhns   +8 more
wiley   +1 more source

Prevalence and functional characterization of anti-interferon autoantibodies in inflammatory myopathies. [PDF]

Rheumatology (Oxford)
Pinal-Fernandez I, Rosen LB, Gomez-Vazquez JL, Casal-Dominguez M, Lee S, Milisenda JC, Pak K, Solanich X, Holland SM, Selva-O'Callaghan A, Mammen AL.   +10 more
europepmc   +1 more source

Autoimmunity and filariasis. Autoantibodies against cytoplasmic cellular proteins in sera of patients with onchocerciasis. [PDF]

, 1993
Jan F. Meilof, Allegonda Van der Lelij, Luis A. Rokeach, Sallie O. Hoch, R J Smeenk   +4 more
openalex   +1 more source

Exposure to occupational inhalants and the risk of developing rheumatoid arthritis: A systematic review and meta‐analysis

Arthritis &Rheumatology, Accepted Article.
Objective: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint pain, swelling, and stiffness. While smoking is a well‐established risk factor for RA, the role of occupational inhalants in RA development is less well recognized.
Qianwen Liu, Xin Song, Emily Mauro, Yuan Jiang, Klementy Shchetynsky, PLars Klareskog, Lars Alfredsson, Xia Jiang   +7 more
wiley   +1 more source

Prolonged In Vitro Exposure to Autoantibodies Against CD38 Impairs the Function and Survival of Human Pancreatic Islets [PDF]

, 2002
Piero Marchetti, Alessandro Antonelli, R Lupi, Lorella Marselli, Poupak Fallahi, Claudia Nesti, Germano Baj, Ele Ferrannini   +7 more
openalex   +1 more source

Prothrombotic Activation of Platelet Pannexin 1 Channels in Antiphospholipid Syndrome

Arthritis &Rheumatology, Accepted Article.
Background ATP is released from platelets through both degranulation and pannexin‐1 (PANX1) channels. ATP then activates P2X receptors to amplify platelet activation via calcium‐dependent signaling. Objective To evaluate the role of platelet PANX1 channels in the pathophysiology of antiphospholipid syndrome (APS), an acquired thrombo‐inflammatory ...
Bruna de Moraes Mazetto Fonseca, Somanathapura K. NaveenKumar, Srilakshmi Yalavarthi, Kavya Sugur, Thalia G. Newman, Claire K. Hoy, Cyrus Sarosh, Jordan K. Schaefer, Ajay Tambralli, Jacqueline A. Madison, Yu Zuo, Fernanda Orsi, Michael Holinstat, Jason S. Knight   +13 more
wiley   +1 more source

Plasma Proteomics Identifies TAOK3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target

Arthritis &Rheumatology, Accepted Article.
Objective Bone destruction associated with active rheumatoid arthritis (RA) remains a major therapeutic challenge, with a lack of reliable molecular markers reflecting bone injury. This study aims to identify novel biomarkers linked to bone destruction in active RA through proteomic analysis, providing new strategies for precise monitoring and targeted
Pengfei Xin, Wenzhen Li, Xinyu A, Jun Shen, Xiaohui Meng, Yanqin Bian, Haihui Han, Zheng Xiang, Lei Ran, Songtao Sun, Jun Xie, Tao Yue, Qi Zhu, Xiaoming Zhang, Lu Xie, Lianbo Xiao   +15 more
wiley   +1 more source

Autoantibody internalization in myositis skeletal muscle: Emerging evidence, mechanistic insights, and therapeutic relevance. [PDF]

Autoimmun Rev
Kirou RA, Pinal-Fernandez I, Mammen AL.
europepmc   +1 more source

Interleukin (IL)‐5, Eosinophils and IL‐5 Pathway Inhibitors in Eosinophilic Granulomatosis with Polyangiitis.

Arthritis &Rheumatology, Accepted Article.
Alvise Berti, Christian Pagnoux
wiley   +1 more source