Results 261 to 270 of about 221,867 (307)
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Rheumatic Disease Clinics of North America, 1988
The diagnosis of SLE is associated with an enlarging assortment of autoantibodies. The presence or absence of particular antibodies influences the confidence with which this diagnosis is made. It is the presence of autoantibodies and the deposit of immunoglobulin that has led to the general conclusion that lupus is an autoimmune disease.
J B, Harley, K K, Gaither
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The diagnosis of SLE is associated with an enlarging assortment of autoantibodies. The presence or absence of particular antibodies influences the confidence with which this diagnosis is made. It is the presence of autoantibodies and the deposit of immunoglobulin that has led to the general conclusion that lupus is an autoimmune disease.
J B, Harley, K K, Gaither
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Current Opinion in Immunology, 1995
Autoantibodies of the IgM, IgG and IgA classes, reactive with a variety of serum proteins, cell surface structures and intracellular structures, are 'naturally' found in all normal individuals. Present in human cord blood and in 'antigen-free' mice, their variable-region repertoire is selected by antigenic structures in the body and remains conserved ...
A, Coutinho +2 more
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Autoantibodies of the IgM, IgG and IgA classes, reactive with a variety of serum proteins, cell surface structures and intracellular structures, are 'naturally' found in all normal individuals. Present in human cord blood and in 'antigen-free' mice, their variable-region repertoire is selected by antigenic structures in the body and remains conserved ...
A, Coutinho +2 more
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Scandinavian Journal of Clinical and Laboratory Investigation, 2001
The characteristics of thyroid autoantibodies are reviewed and new assays for the autoantibodies described, in particular point of care (POC) tests for thyroid peroxidase (TPO) autoantibodies and for thyroglobulin (Tg) autoantibodies. These POC tests depend on the ability of the autoantibodies to inhibit gold labelled human monoclonal antibodies ...
Saravanan, P, Dayan, CM
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The characteristics of thyroid autoantibodies are reviewed and new assays for the autoantibodies described, in particular point of care (POC) tests for thyroid peroxidase (TPO) autoantibodies and for thyroglobulin (Tg) autoantibodies. These POC tests depend on the ability of the autoantibodies to inhibit gold labelled human monoclonal antibodies ...
Saravanan, P, Dayan, CM
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Current Diabetes Reports, 2016
Islet autoantibodies are the main markers of pancreatic autoimmunity in type 1 diabetes (T1D). Islet autoantibodies recognize insulin (IAA), glutamic acid decarboxylase (GADA), protein phosphatase-like IA-2 (IA-2A), and ZnT8 (ZnT8A), all antigens that are found on secretory granules within pancreatic beta cells.
Vito, Lampasona, Daniela, Liberati
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Islet autoantibodies are the main markers of pancreatic autoimmunity in type 1 diabetes (T1D). Islet autoantibodies recognize insulin (IAA), glutamic acid decarboxylase (GADA), protein phosphatase-like IA-2 (IA-2A), and ZnT8 (ZnT8A), all antigens that are found on secretory granules within pancreatic beta cells.
Vito, Lampasona, Daniela, Liberati
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Clinics in Laboratory Medicine, 2004
The autoantibody assays that exist and that are being refined are of increasing importance to a broad spectrum of endocrine disorders. This is particularly true for type IA diabetes, which is one of the best-studied organ-specific autoimmune diseases. Autoantibodies are used as valuable markers in prediction and prevention studies of type IA diabetes ...
Devasenan, Devendra +2 more
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The autoantibody assays that exist and that are being refined are of increasing importance to a broad spectrum of endocrine disorders. This is particularly true for type IA diabetes, which is one of the best-studied organ-specific autoimmune diseases. Autoantibodies are used as valuable markers in prediction and prevention studies of type IA diabetes ...
Devasenan, Devendra +2 more
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Clinica Chimica Acta, 2006
The nucleosome is a large protein-nucleic acid complex involved in DNA packing and in controlling genetic information. Under circumstances described below, this component, normally sequestered in the cell nucleus, is released into the extracellular milieu and then is easily accessible to cells of the immune system.
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The nucleosome is a large protein-nucleic acid complex involved in DNA packing and in controlling genetic information. Under circumstances described below, this component, normally sequestered in the cell nucleus, is released into the extracellular milieu and then is easily accessible to cells of the immune system.
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ICA512 Autoantibody Radioassay
Diabetes, 1995As part of a general program of screening islet expression libraries we have identified a clone from a λgt11 human islet expression library that reacts with human diabetic sera and, upon sequencing, was determined to be the neuroendocrine islet autoantigen ICA512 (islet cell antigen 512).
R, Gianani +6 more
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Archives of Dermatology, 1976
To the Editor.— The association of vitiligo with a number of organspecific autoimmune disorders, such as pernicious anemia, 1 hyperthyroidism and hypothyroidism, 2 Addison disease, 3 and diabetes mellitus 4 is well known. An increased incidence of organ-specific antibodies was reported in patients with vitiligo, 5,6 but, more recently, no ...
BETTERLE, CORRADO +6 more
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To the Editor.— The association of vitiligo with a number of organspecific autoimmune disorders, such as pernicious anemia, 1 hyperthyroidism and hypothyroidism, 2 Addison disease, 3 and diabetes mellitus 4 is well known. An increased incidence of organ-specific antibodies was reported in patients with vitiligo, 5,6 but, more recently, no ...
BETTERLE, CORRADO +6 more
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Neurologic Clinics, 2004
Recent advances in neuroimmunology have led to improvements in the pathogenesis, diagnosis, prognosis, and treatment of many neuromuscular disorders. The value of autoantibody testing is increasing steadily in neurologic practice. Not all antibodies have a high yield in diagnosis. In some disorders, such as generalized adult onset of myasthenia gravis,
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Recent advances in neuroimmunology have led to improvements in the pathogenesis, diagnosis, prognosis, and treatment of many neuromuscular disorders. The value of autoantibody testing is increasing steadily in neurologic practice. Not all antibodies have a high yield in diagnosis. In some disorders, such as generalized adult onset of myasthenia gravis,
openaire +2 more sources