Results 271 to 280 of about 139,183 (310)
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Archives of Dermatology, 1976
To the Editor.— The association of vitiligo with a number of organspecific autoimmune disorders, such as pernicious anemia, 1 hyperthyroidism and hypothyroidism, 2 Addison disease, 3 and diabetes mellitus 4 is well known. An increased incidence of organ-specific antibodies was reported in patients with vitiligo, 5,6 but, more recently, no ...
BETTERLE, CORRADO +6 more
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To the Editor.— The association of vitiligo with a number of organspecific autoimmune disorders, such as pernicious anemia, 1 hyperthyroidism and hypothyroidism, 2 Addison disease, 3 and diabetes mellitus 4 is well known. An increased incidence of organ-specific antibodies was reported in patients with vitiligo, 5,6 but, more recently, no ...
BETTERLE, CORRADO +6 more
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Current Opinion in Supportive & Palliative Care, 2016
Over the last 20 years, several neurological conditions have been identified which appear to be caused directly by autoantibodies targeting receptors, ion channels and related proteins on neuronal or glial cells. Neuroimmune interactions are now accepted contributors to chronic pain conditions.
Dawes, J, Vincent, A
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Over the last 20 years, several neurological conditions have been identified which appear to be caused directly by autoantibodies targeting receptors, ion channels and related proteins on neuronal or glial cells. Neuroimmune interactions are now accepted contributors to chronic pain conditions.
Dawes, J, Vincent, A
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Scandinavian Journal of Rheumatology, 1997
Autoantibody determinations are frequently used by rheumatologists to establish the diagnosis or assess follow up clinical status in patients with connective tissue diseases. Such autoantibodies are often presumed to have harmful effects, particularly since some such as anti-native DNA or anti-Ro have frequently been related to tissue damage or to ...
Williams RC +2 more
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Autoantibody determinations are frequently used by rheumatologists to establish the diagnosis or assess follow up clinical status in patients with connective tissue diseases. Such autoantibodies are often presumed to have harmful effects, particularly since some such as anti-native DNA or anti-Ro have frequently been related to tissue damage or to ...
Williams RC +2 more
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Nature Reviews Rheumatology, 2018
The discovery of novel autoantigen systems related to idiopathic inflammatory myopathies (collectively referred to as myositis) in adults and children has had major implications for the diagnosis and management of this group of diseases across a wide range of medical specialties.
Sarah L Tansley, Neil McHugh
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The discovery of novel autoantigen systems related to idiopathic inflammatory myopathies (collectively referred to as myositis) in adults and children has had major implications for the diagnosis and management of this group of diseases across a wide range of medical specialties.
Sarah L Tansley, Neil McHugh
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Epilepsia, 2011
SummaryIn a substantial number of patients with epilepsy, the etiology of the seizure disorder remains unknown. In recent years, the detection of autoantibodies has contributed to the etiologic understanding of a substantial number of so far unexplained epilepsies.
Christian G. Bien, Ingrid E. Scheffer
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SummaryIn a substantial number of patients with epilepsy, the etiology of the seizure disorder remains unknown. In recent years, the detection of autoantibodies has contributed to the etiologic understanding of a substantial number of so far unexplained epilepsies.
Christian G. Bien, Ingrid E. Scheffer
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Autoantibodies and their idiotypes
Current Opinion in Rheumatology, 1991Antinuclear antibodies occur prominently in systemic lupus erythematosus and serve as markers of underlying pathogenetic disturbances. Although these antibodies display features indicative of genetic control and in vivo selection by self-antigen, other mechanisms shaping the B-cell repertoire may influence their production.
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Autoantibodies to Ribonucleoproteins
Clinics in Rheumatic Diseases, 1985Presently we recognize at least 12 different autoantibodies that involve ribonucleoproteins as antigens in patients with SLE and other rheumatic diseases. Such autoantibodies have a number of clinically useful diagnostic associations. Moreover, they have proved to be powerful tools for understanding the structure and function of a variety of cellular ...
Tsuneyo Mimori, John A. Hardin
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Endocrinology and Metabolism Clinics of North America, 2001
Although assays to detect thyroid autoantibodies have been available for more than 40 years, their place in the clinical management of thyroid disease has remained controversial; however, novel automated detection techniques using recombinant antigens are increasing the sensitivity and specificity of the assays, particularly for antibodies to the TSH ...
Saravanan, P, Dayan, CM
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Although assays to detect thyroid autoantibodies have been available for more than 40 years, their place in the clinical management of thyroid disease has remained controversial; however, novel automated detection techniques using recombinant antigens are increasing the sensitivity and specificity of the assays, particularly for antibodies to the TSH ...
Saravanan, P, Dayan, CM
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Diabetes, 2005
Islet cell autoantibodies are strongly associated with the development of type 1 diabetes. The appearance of autoantibodies to one or several of the autoantigens—GAD65, IA-2, or insulin—signals an autoimmune pathogenesis of β-cell killing. A β-cell attack may be best reflected by the emergence of autoantibodies dependent on the genotype risk factors ...
Åke Lernmark +3 more
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Islet cell autoantibodies are strongly associated with the development of type 1 diabetes. The appearance of autoantibodies to one or several of the autoantigens—GAD65, IA-2, or insulin—signals an autoimmune pathogenesis of β-cell killing. A β-cell attack may be best reflected by the emergence of autoantibodies dependent on the genotype risk factors ...
Åke Lernmark +3 more
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Rheumatic Disease Clinics of North America, 1992
The antinuclear and antinucleolar antibodies found in patients with scleroderma are discussed. Many of the autoantigens have been characterized, the cDNA cloned and the epitopes defined. Many of the more common autoantigens are DNA-binding proteins, which are very important in transcription and in cell division.
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The antinuclear and antinucleolar antibodies found in patients with scleroderma are discussed. Many of the autoantigens have been characterized, the cDNA cloned and the epitopes defined. Many of the more common autoantigens are DNA-binding proteins, which are very important in transcription and in cell division.
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