Results 111 to 120 of about 195,106 (347)

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki, Alireza Amindarolzarbi, Tsion Abdi, John Clarke, Michael Hughes, Ami A. Shah, Zsuzsanna H. McMahan   +6 more
wiley   +1 more source

Elevation of TP53 Autoantibody Prior to CA125 in Preclinical Invasive Epithelial Ovarian Cancer

Clinical Cancer Research, 2017
Purpose: The TP53 tumor-suppressor gene is mutated in >95% of high-grade serous ovarian cancers. Detecting an autologous antibody response to TP53 that might improve early detection.
Wei-Lei Yang, A. Gentry-Maharaj, Archana R. Simmons, A. Ryan, E. Fourkala, Zhen Lu, K. Baggerly, Yang Zhao, Karen H. Lu, D. Bowtell, I. Jacobs, S. Skates, Wei-Yang He, U. Menon, R. Bast   +14 more
semanticscholar   +1 more source

Autoantibody standardization in The Netherlands.

, 2009
Item does not contain fulltextSeveral initiatives have been undertaken, independent of the European Autoantibody Standardization Initiative (EASI), to standardize autoantibodies in The Netherlands.
Hamann, D., Kallenberg, C, Klasen, I.S., Ronald Derksen, Derksen, Ronald, Ina Klasen, Smeenk, Ruud, Dörte Hamann, Tervaert, Jan Willem Cohen, Limburg, P., Smeenk, R, Limburg, P, Pieter Limburg, Hamann, D, Derksen, R, Herbert Hooijkaas, Damoiseaux, J., Damoiseaux, Jan, Ruud Smeenk, Hooijkaas, H., Shoenfeld, Y, Jan Willem Cohen Tervaert, Hooijkaas, Herbert, Derksen, R., Kallenberg, C.G.M., Smeenk, R., Cees Kallenberg, Tervaert, J.W., Jan Damoiseaux, Hamann, Dorte, Kallenberg, Cees, Tervaert, JWC, Hooijkaas, H (Herbert), Klasen, Ina, Limburg, Pieter, Klasen, I, Gershwin, ME, Damoiseaux, J   +37 more
core   +1 more source

Determinants of Body Mass Index in Early Systemic Sclerosis: Implications for Nutritional Risk Stratification

Arthritis Care &Research, EarlyView.
Objective Gastrointestinal (GI) involvement can lead to malnutrition in patients with systemic sclerosis (SSc). Body mass index (BMI) remains the most widely used marker to screen nutritional status. We aimed to identify predictors of lower BMI in patients with SSc. Methods Patients with SSc from a prospective US cohort meeting 2013 American College of
Ali Y. Ayla, Meng Zhang, Bingrui Chen, Claudia Pedroza, Brian Skaug, Maureen Mayes, Michael Hughes, Shervin Assassi, Zsuzsanna H. McMahan   +8 more
wiley   +1 more source

Prognostic significance of six autoantibodies in esophageal squamous cell carcinoma: A prospective multi‐institutional study

Annals of Gastroenterological Surgery
Aim Serum autoantibodies have been reported to react with tumor‐associated antigens in various cancers. This study evaluated the diagnostic and prognostic significance of six autoantibody panels in esophageal squamous cell carcinoma.
Fumiaki Shiratori, Naoto Fujiwara, Yasuaki Nakajima, Koji Otsuka, Masahiko Murakami, Satoru Matsuda, Hirofumi Kawakubo, Keita Takahashi, Yuichiro Tanishima, Daiji Oka, Shunichi Ito, Kosuke Narumiya, Osamu Aramaki, Tadatoshi Takayama, Takashi Suzuki, Satoshi Yajima, Hideaki Shimada   +16 more
doaj   +1 more source

The juvenile idiopathic inflammatory myopathies: pathogenesis, clinical and autoantibody phenotypes, and outcomes

Journal of Internal Medicine, 2016
The aim of this review was to summarize recent advances in the understanding of the clinical and autoantibody phenotypes, their associated outcomes and the pathogenesis of the juvenile idiopathic inflammatory myopathies (JIIMs).
L. Rider, K. Nistala
semanticscholar   +1 more source

Facial Cosmetic Therapy Use Among Patients With Systemic Sclerosis: An Australian Cohort Study

Arthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) is associated with numerous facial manifestations for which patients may engage in cosmetic therapies. It is unclear how patients with SSc use these therapies. This study sought to characterize patient engagement and experiences with cosmetic therapies for SSc‐related and non‐SSc–related facial changes.
Zachary Warren, Diane Apostolopoulos, Gene‐Siew Ngian, Amanda M. Saracino, Laura Ross, Nava Ferdowsi, Jennifer Walker, Cindy Hall, Kim Griggs, Susanna Proudman, Wendy Stevens, Joanne Sahhar   +11 more
wiley   +1 more source

Genetic imprinting of autoantibody repertoires in systemic lupus erythematosus patients [PDF]

, 2008
Systemic lupus erythematosus (SLE) is an autoimmune disease distinguished by great heterogeneity in clinical manifestations and autoantibody expression.
Goodyear, C.S., Silverman, G.J., Ginzler, E.M., R. Srikrishnan, B. P. Tsao, G. J. Silverman, E. M. Ginzler, K. A. Andrews, Germar, K., K. Germar, Srikrishnan, R., C. S. Goodyear, Tsao, B.P., Andrews, K.A.   +13 more
core   +2 more sources

Capillary blood islet autoantibody screening for identifying pre-type 1 diabetes in the general population: design and initial results of the Fr1da study

BMJ Open, 2016
Introduction Type 1 diabetes can be diagnosed at an early presymptomatic stage by the detection of islet autoantibodies. The Fr1da study aims to assess whether early staging of type 1 diabetes (1) is feasible at a population-based level, (2) prevents ...
J. Raab, F. Haupt, M. Scholz, C. Matzke, K. Warncke, K. Lange, R. Assfalg, Katharina Weininger, Susanne Wittich, Stephanie Löbner, A. Beyerlein, U. Nennstiel-Ratzel, M. Lang, O. Laub, D. Dunstheimer, E. Bonifacio, P. Achenbach, C. Winkler, A. Ziegler   +18 more
semanticscholar   +1 more source

[Which clinical symptoms suggest distinct autoantibody measurements?]

, 2010
The detection of autoantibodies is an important cornerstone in the diagnosis of systemic autoimmune disorders such as autoimmune connectivitides and small vessel vasculitides.
Seitz, Michael
core