Results 101 to 110 of about 78,014 (306)

Initial autoantibody targets in the pre-diagnosis cohort.

, 2013
(A) The front (black) bars show the number of patients developing antibodies to respective antigen as their initial single autoantibody specificity. The middle (dark gray) bars show the number of patients with antibodies to the respective antigen in ...
Benjamin F. Bruner (366508), Michael P. Keith (366510), Latisha D. Heinlen (366506), Micah T. McClain (200348), Colin C. Edgerton (366509), Judith A. James (149082), John B. Harley (104190), Lauren L. Ritterhouse (366507)   +7 more
core   +1 more source

Autoantibody Positivity in Children with Chronic Diarrhea

, 2020
Aim:We aimed to determine the frequency of autoantibody antinuclear (ANA), peripheral anti-neutrophil cytoplasmic antibody (p-ANCA), anti-Saccharomyces cerevisiae antibody (ASCA), anti-pancreatic exocrine gland antibody (PAb), goblet cell antibody (GAb ...
Elif Azarsız, Funda Çetin, Çetin, Funda, Aslı Aslan, Neslihan Karaca, Ecevit, Çiğdem Ömür, Aksu, Güzide, Azarsız, Elif, Aslan, Aslı, Çiğdem Ecevit, Necil Kütükçüler, Tuhan, Hale, Güzide Aksu, Karaca, Neslihan Edeer, Hale Tuhan   +14 more
core   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Binding patterns of glycine receptor autoantibodies are related to clinical syndromes

Acta Neuropathologica Communications
Patients diagnosed with the rare autoimmune disease Stiff Person Syndrome (SPS) or the more severe form Progressive Encephalomyelitis with Rigidity and Myoclonus (PERM) as well as patients with encephalitis or epilepsy may harbor autoantibodies against ...
Inken Piro, Anna-Lena Wiessler, Eleni Kakavela, Betül Baykan, Erdem Tüzün, Carmen Villmann, Claudia Sommer   +6 more
doaj   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

Extrapancreatic autoantibody profiles in type I diabetes.

, 2012
Type I diabetes (T1D) is an autoimmune disease characterized by destruction of insulin-producing β-cells in the pancreas. Although several islet cell autoantigens are known, the breadth and spectrum of autoantibody targets has not been fully explored ...
Ahmad Bayat, Evan E. Lebovitz (135491), Kathleen E. Bren (135492), Marian Rewers (135498), Peter D Burbelo, Scott Paviol, Peter D. Burbelo (135490), Michael J. Iadarola (135502), Katherine J Barriga, Marian Rewers, Michael J Iadarola, Kathleen E Bren, Ahmad Bayat (135493), Scott Paviol (135494), David M Harlan, Evan E Lebovitz, Katherine J. Barriga (135496), David M. Harlan (135500), Janet M Wenzlau, Janet M. Wenzlau (135495)   +19 more
core   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

The value of parotid sialography in the diagnosis and staging of Sjogren's syndrome

Journal of Dental Sciences
Background/purpose: 2016 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) primary Sjögren's syndrome (SS) diagnostic criteria did not incorporate radiographic examination while staging SS according to salivary gland imaging
Yutian Wang, Xiaoyan Xie, Ying Han, Xingyun Liu, Qianyun Guo, Lei Zhang, Xinyi Ni, Hongwei Liu   +7 more
doaj   +1 more source

Targeting METTL3 Attenuates Thyroid Inflammatory Injury by Restoring Th17/Treg Balance through a YTHDC2‐m6A‐Dependent KDR/VEGFA Loop

Advanced Science, EarlyView.
METTL3‐mediated m6A modification stabilizes KDR/Kdr mRNA through YTHDC2, amplifying the VEGFA‐KDR feedback loop and disturbing Th17/Treg balance. This pathway promotes persistent inflammation and tissue damage in patients with AIT, and inhibiting the METTL3‐KDR axis effectively disrupts this circuit, alleviating thyroid tissue injury and disease ...
Qingyi Hu, Huan Liu, Anwen Ren, Zimei Tang, Jie Tan, Wen Yang, Jie Ming, Tao Huang   +7 more
wiley   +1 more source