Results 141 to 150 of about 137,333 (337)
Arthritis &Rheumatology, Accepted Article.Objectives Rheumatoid arthritis (RA) is usually preceded and likely mediated by autoantibodies to citrullinated proteins (ACPAs) that recognize citrulline residues on multiple proteins. Conversion of arginine into citrulline is performed by enzymes called peptidyl arginine deiminases (PADs).
Philippe P. Pagni +10 more
wiley +1 more source
Arthritis &Rheumatology, Accepted Article.Objectives The effect of the shared epitope (SE), and valine at position 11 (Val11) of HLA‐DRB1, on the activation of CD4+ T cells, is expected to be diminished by abatacept, a co‐stimulation blocker. However, published evidence on the value of genetic stratification for abatacept treatment is conflicting.
Chuan Fu Yap +14 more
wiley +1 more source
Arthritis &Rheumatology, Accepted Article.Objective To assess risks of adverse pregnancy outcomes (APO) in a contemporary cohort of women with systemic sclerosis (SSc) in relation to the timing of SSc diagnosis and by parity. Methods From the nationwide Swedish Medical Birth Register, we assembled pregnancies with births in women with SSc and in comparator women from the general population ...
Weng Ian Che +5 more
wiley +1 more source
Autoantibody response towards chromatin in patients with juvenile idiopathic arthritis
Arthritis &Rheumatology, Accepted Article.Objective Juvenile idiopathic arthritis (JIA) patients frequently exhibit antinuclear antibodies (ANAs), but the specific antigen target recognized by them and the presence of additional autoantibody specificities in JIA patients remains elusive. Methods Plasma samples from 110 untreated patients with active JIA, as well as from 14 children with ...
Viola Pitkänen +13 more
wiley +1 more source
Arthritis &Rheumatology, Accepted Article.Objectives Growing evidence suggests farming and agricultural pesticide use may be associated with rheumatoid arthritis (RA), but few studies have examined specific pesticides and RA among farm women, who may personally use pesticides or be indirectly exposed.
Christine G. Parks +7 more
wiley +1 more source
Immunological reactivity in ankylosing spondylitis. Circulating immunoblasts, autoantibodies, and immunoglobulins. [PDF]
, 1976 A A Eghtedari, Paul J. Davis, P A Bacon
openalex +1 more source
B cells and systemic sclerosis interstitial lung disease
Arthritis &Rheumatology, Accepted Article.Interstitial lung disease is an important complication of systemic sclerosis (SSc‐ILD) with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to FDA‐approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of interstitial lung diseases of other systemic autoimmune ...
Nina Goldman +2 more
wiley +1 more source
Autoantibodies detected in rabbits hyperimmunized with group A, C, and G streptococcal vaccines [PDF]
, 1977 Doina Onicǎ +4 more
openalex +1 more source
Alu Overexpression Leads to an Increased Double‐stranded RNA Signature in Dermatomyositis
Arthritis &Rheumatology, Accepted Article.Objective Dermatomyositis is an autoimmune condition characterized by a high interferon signature of unknown etiology. Because coding sequences constitute <1.2% of our genomes, there is a need to explore the role of the non‐coding genome in disease pathogenesis.
Rayan Najjar +2 more
wiley +1 more source