Results 151 to 160 of about 228,187 (396)

The National Academies’ 2024 Diagnostic Criteria for Long COVID: Concerns That Could Affect the Rheumatology Community

Arthritis &Rheumatology, EarlyView.
Leonard H. Calabrese, Michael Putman, Jeffrey A. Sparks, Zachary Wallace, Alfred H. J. Kim, Kevin L. Winthrop, Cassandra Calabrese   +6 more
wiley   +1 more source

Mucosal‐associated invariant T cells in rheumatic diseases.

Arthritis &Rheumatology, Accepted Article.
Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor (TCR) and restriction by the MHC class I‐related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines. Upon activation, MAIT cells rapidly produce pro‐inflammatory cytokines,
Manon Lesturgie‐Talarek, Virginie Gonzalez, Lucie Beaudoin, Noémie Sénot, Corinne Miceli‐Richard, Yannick Allanore, Agnès Lehuen, Jerôme Avouac   +7 more
wiley   +1 more source

Autoantibodies Against β1‐Adrenoceptor Exaggerated Ventricular Remodeling by Inhibiting CTRP9 Expression

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Autoantibodies against the second extracellular loop of the β1‐adrenoceptor (β1‐AA) act similarly to agonist of β1‐adrenergic receptor, which plays an important role in the pathophysiological characteristics of ventricular remodeling. Recently,
Yunhui Du, Shihan Zhang, Haicun Yu, Ye Wu, Ning Cao, Wen Wang, Wenli Xu, Yuming Li, Huirong Liu   +8 more
doaj   +1 more source

Autoantibody Epitope Spreading in the Pre-Clinical Phase Predicts Progression to Rheumatoid Arthritis

PLoS ONE, 2012
Rheumatoid arthritis (RA) is a prototypical autoimmune arthritis affecting nearly 1% of the world population and is a significant cause of worldwide disability.
J. Sokolove, J. Sokolove, Reuven Bromberg, Reuven Bromberg, K. Deane, Lauren J. Lahey, Lezlie A. Derber, P. Chandra, J. Edison, W. Gilliland, R. Tibshirani, J. Norris, V. Holers, William H. Robinson, William H. Robinson   +14 more
semanticscholar   +1 more source

Editorial: Autoantibodies [PDF]

Frontiers in Immunology, 2019
Holmdahl, Rikard, Nimmerjahn, Falk, Ludwig, Ralf J.   +2 more
openaire   +3 more sources

Expert Perspective: Diagnosis and Treatment of Castleman Disease

Arthritis &Rheumatology, Accepted Article.
Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen, Lu Zhang, David C. Fajgenbaum   +2 more
wiley   +1 more source

Anti-idiotypic Antibodies against BP-IgG Prevent Type XVII Collagen Depletion

Frontiers in Immunology, 2017
Bullous pemphigoid (BP) mainly targets type XVII collagen (COL17). Intravenous immunoglobulin (IVIg) is used to treat numerous autoimmune diseases, including BP. The major mechanism of action for IVIG is thought to be its immunomodulatory effect. However,
Mayumi Kamaguchi, Mayumi Kamaguchi, Hiroaki Iwata, Yuiko Mori, Ellen Toyonaga, Hideyuki Ujiie, Yoshimasa Kitagawa, Hiroshi Shimizu   +7 more
doaj   +1 more source

Studies on Autoantibodies in Human Sera [PDF]

, 1953
Alexander S. Wiener, Eve B. Gordon, Carol Gallop   +2 more
openalex   +1 more source

Amyloid‐Related Imaging Abnormality (ARIA) Beyond the APOE‐ε4 Allele

Chronic Diseases and Translational Medicine, EarlyView.
Mechanism of action of monoclonal antibodies targeting Aβ in the treatment of AD. (A) Targets of various mAbs. (B) Mechanism of monoclonal antibody‐mediated clearance of Aβ. mAbs facilitate the clearance of Aβ by enhancing microglial‐mediated phagocytosis through the upregulation of TREM2 expression.
Valentinus Besin, Farizky Martriano Humardani, Fenny Lanawati Yudiarto, Paulus Anam Ong, Sulistyo Emantoko Dwi Putra, Ratih Asmana Ningrum   +5 more
wiley   +1 more source

Limited AT1 Receptor Internalization Is a Novel Mechanism Underlying Sustained Vasoconstriction Induced by AT1 Receptor Autoantibody From Preeclampsia

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Angiotensin II type 1 receptor (AT1R) autoantibody (AT1‐AA) was first identified as a causative factor in preeclampsia. Unlike physiological ligand angiotensin II (Ang II), AT1‐AA can induce vasoconstriction in a sustained manner, causing a ...
Jingwei Bian, Jinghui Lei, Xiaochen Yin, Pengli Wang, Ye Wu, Xiaoli Yang, Li Wang, Suli Zhang, Huirong Liu, Michael L. X. Fu   +9 more
doaj   +1 more source