Dysregulation of U12‐Type Splicing in Lupus Neutrophils
Abstract. Objective Neutrophil dysfunction is a hallmark of systemic lupus erythematosus (SLE), but its molecular basis remains unclear. This study explores transcriptional and post‐transcriptional changes in low‐density granulocytes (LDGs), a proinflammatory neutrophil subset expanded in SLE, focusing on NADPH oxidase (Nox) function and minor intron ...
Luz P. Blanco +11 more
wiley +1 more source
Letter to the Editor Regarding: Cognitive Function and Proteomic Changes in Patients with Autoantibody-Positive Neurodegenerative Dementia. [PDF]
Lu X, Shen X.
europepmc +1 more source
Folinic Acid Supplementation During Pregnancy in Two Women with Folate Receptor Alpha Autoantibodies: Potential Prevention of Autism Spectrum Disorder in Offspring [PDF]
Claudio Giorlandino +3 more
openalex +1 more source
Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou +6 more
wiley +1 more source
The thyrotropin receptor structure and interactions with autoantibodies. [PDF]
Rees Smith B +2 more
europepmc +1 more source
O55. Prevalence of Autoantibodies to Hmgcr in Myositis Patients [PDF]
Zoë Betteridge +6 more
openalex +1 more source
Abstract Objective This study aimed to identify risk factors and develop a predictive scoring system for autoimmune‐associated epilepsy in subjects with autoimmune encephalitis presenting with new onset refractory status epilepticus (NORSE). Methods This retrospective, multicenter, cohort study included subjects who presented with NORSE at the onset of
Simona Lattanzi +50 more
wiley +1 more source
Autoantibody internalization in myositis skeletal muscle: Emerging evidence, mechanistic insights, and therapeutic relevance. [PDF]
Kirou RA, Pinal-Fernandez I, Mammen AL.
europepmc +1 more source
266 Human autoantibodies from children with movement and psychiatric disorders target the extracellular n-terminus of dopamine-2 receptor [PDF]
Nese Sinmaz +8 more
openalex +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source

