Objective Anti‐citrullinated protein antibodies (ACPAs) in rheumatoid arthritis (RA) can be promiscuous, with cross‐reactive binding to many antigens containing short motifs, or private with little cross‐reactivity. Also, ACPA reactivity patterns differ among RA patients, including for motif‐containing epitopes in important self‐antigens like collagen ...
S. Janna Bashar +4 more
wiley +1 more source
Clinical Characteristics in Swedish Children With and Without Autoantibodies at the Time of Type 1 Diabetes Diagnosis. [PDF]
Hedlund E +9 more
europepmc +1 more source
Structure and dynamics of the autoantigen GAD65 in complex with the human autoimmune polyendocrine syndrome type 2-associated autoantibody b96.11 [PDF]
Susanne H. D. Ständer +18 more
openalex +1 more source
IgG human monoclonal anti-DNA autoantibodies from patients with systemic lupus erythematosus [PDF]
Thomas Winkler +2 more
openalex +1 more source
Biomarkers of Lupus Nephritis Histopathology: Where Do We Stand?
Objective Lupus nephritis (LN) is characterized by a variable disease course, necessitating continuous monitoring. There is an urgent need to identify non‐invasive biomarkers. By reviewing and critically assessing the quality of existing studies on LN biomarkers correlating with histopathology, we here explore the challenges in promoting their use in ...
Valentina Querin +11 more
wiley +1 more source
The thyrotropin receptor structure and interactions with autoantibodies. [PDF]
Rees Smith B +2 more
europepmc +1 more source
DKA in a toddler negative to type 1 diabetes autoantibodies: unusual presentation of Kearn–Sayre syndrome [PDF]
Annalisa Deodati +7 more
openalex +1 more source
Objective Complement component 4 (C4), encoded by C4A and C4B within the major histocompatibility complex (MHC) on chromosome 6, regulates the immune response and clears immune complexes. Variable copy number (CN) of C4 genes and retroviral HERV‐K element influence its function.
Javier Martínez‐López +23 more
wiley +1 more source
Autoantibody internalization in myositis skeletal muscle: Emerging evidence, mechanistic insights, and therapeutic relevance. [PDF]
Kirou RA, Pinal-Fernandez I, Mammen AL.
europepmc +1 more source

