Results 321 to 330 of about 228,187 (396)

G protein‐coupled receptor‐mediated autophagy in health and disease

British Journal of Pharmacology, EarlyView.
G protein‐coupled receptors (GPCRs) constitute the largest and most diverse superfamily of mammalian transmembrane proteins. These receptors are involved in a wide range of physiological functions and are targets for more than a third of available drugs in the market. Autophagy is a cellular process involved in degrading damaged proteins and organelles
Devrim Öz‐Arslan, Zeynep Aslıhan Durer, Beki Kan   +2 more
wiley   +1 more source

Presence of autoantibody for phospholipase inhibitory protein, lipomodulin, in patients with rheumatic diseases.

, 1981
Fusao Hirata, R del Carmine, Charles A. Nelson, J Axelrod, E Schiffmann, A Warabi, Angel L. De Blas, Marshall W. Nirenberg, Vincent C. Manganiello, M Vaughan, Shunichi Kumagai, I Green, John L. Decker, A D Steinberg   +13 more
openalex   +1 more source

Potential and pitfalls of measuring circulating anti-nephrin autoantibodies in glomerular diseases. [PDF]

Clin Kidney J
Hengel FE, Huber TB, Tomas NM.
europepmc   +1 more source

The Epidemiology of Chronic Urticaria in Cape Town, South Africa: A Review of Two Tertiary Referral Centers

Allergy, EarlyView.
Cascia Day, Mimi Deetlefs, Lovemore Mapahla, Yejin Jang, Qiqa Gusha‐Mhlekude, Sicelo Ntuli, Balican Hlungwani, Susanna Kannenberg, Emma Kruger, Ndapewa Ambondo, Willem Visser, Thuraya Isaacs, Rannakoe Lehloenya, Jonny Peter   +13 more
wiley   +1 more source

GNS561 (ezurpimtrostat), a small basic lipophilic molecule, prevents lupus phenotype in a pristane‐induced lupus mouse model

British Journal of Pharmacology, EarlyView.
Background and Purpose Systemic lupus erythematosus is an autoimmune, multisystemic disease affecting all organs in the body. Accrued evidence has elucidated a role for autophagy in the onset and severity of systemic lupus erythematosus. The antimalarial drug hydroxychloroquine constitutes the cornerstone of standard of care for systemic lupus ...
Eya Toumi, Eloïne Bestion, Muriel Militello, Hubert Lepidi, Anne Plauzolles, Nathalie Bardin, Daniel Bertin, Laurent Chiche, Jean‐Louis Mege, Philippe Halfon, Soraya Mezouar   +10 more
wiley   +1 more source

Supersulfide metabolome of exhaled breath condensate applied as diagnostic biomarkers for esophageal cancer

Cancer Science, Volume 116, Issue 4, Page 1023-1033, April 2025.
This study evaluated the potential of sulfur metabolites as biomarkers for esophageal cancer using blood and exhaled breath condensate (EBC) samples. Absolute quantification analysis revealed elevated levels of cysteine hydropersulfide (CysSSH) and homocysteine hydropersulfide (HomoCysSSH) in patients with esophageal cancer, with HomoCysSSH in plasma ...
Seji Asamitsu, Yohei Ozawa, Hiroshi Okamoto, Seiryo Ogata, Tetsuro Matsunaga, Jun Yoshitake, Kazuki Fusegawa, Yusuke Taniyama, Chiaki Sato, Hirotaka Ishida, Takaaki Abe, Hozumi Motohashi, Takaaki Akaike, Takashi Kamei   +13 more
wiley   +1 more source

Molecular Mimicry Drives Locally Produced Autoantibodies in Subarachnoid Neurocysticercosis. [PDF]

Open Forum Infect Dis
Guzmán JJ, Bah A, Bennuru S, Harrison S, Nash TE, Sciurba J, Thumm L, Nutman TB, O'Connell EM.   +8 more
europepmc   +1 more source

Management of Maternal Hypothyroidism in Pregnancy: A Danish Regional Study

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Hypothyroidism in pregnant women must be carefully managed to prevent complications. The aim of this study was to evaluate compliance with clinical recommendations for the monitoring and treatment of hypothyroidism in pregnant women and to assess the clinical action upon each biochemical monitoring at different time points in ...
Karoline Schack, Line Meyer Laustsen, Randi Ziska Sørensen, Maja Hjelm Lundgaard, Nanna Maria Uldall Torp, Jesper Karmisholt, Stine Linding Andersen   +6 more
wiley   +1 more source

Autoimmune bullous diseases: pathogenesis and clinical management. [PDF]

Mol Biomed
Feng X, Zheng H, Wang M, Wang Y, Zhou X, Zhang X, Li J, Xiao Y, Wei M, Li X, Hashimoto T, Li J, Li W.   +12 more
europepmc   +1 more source

Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women

Clinical Endocrinology, EarlyView.
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan, James M. Hawley, Leanne Cussen, Ali Abbara, Sophie A. Clarke, Punith Kempegowda, Rima K. Dhillon‐Smith, Puja Thadani, Maureen Busby, Lucy Owusu‐Darkwah, Rachel Marrington, W. Colin Duncan, Robert K. Semple, Richard Quinton, Michael W. O'Reilly   +14 more
wiley   +1 more source