Results 131 to 140 of about 91,538 (308)
Frontiers in ImmunologyIntroductionRed pulp macrophages (RPMs) play a central role in iron recycling and immune regulation within the spleen, yet optimized methods for the isolation and characterization of pig RPM remain limited.MethodsWe compared two approaches for isolating ...
Phu Chi Vu +7 more
doaj +1 more source
Advanced Science, EarlyView.A biomimetic hydrogel (HPC@Gel) was developed for traumatic brain injury repair by combining oxygen‐carrying hemoglobin nanoparticles and anti‐inflammatory carbon quantum dots within a brain‐like matrix. The system alleviated hypoxia, reduced harmful neuroimmune signaling, protected neurons, supported neural regeneration, and improved neurological and ...
Peng Liu +12 more
wiley +1 more source
Advanced Science, EarlyView.Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung +39 more
wiley +1 more source
Time-Since-Deposition Signatures for Canine Blood Based on Cellular Autofluorescence
Veterinary SciencesAnimal cruelty investigations can be hampered by not knowing when a biological sample was deposited at a crime scene, i.e., the sample’s time-since-deposition (TSD). The goal of this study was to characterize a new signature system for estimating the TSD
Alysia Townsley +5 more
doaj +1 more source
Advanced Science, EarlyView.ROS‐Responsive H2S Hydrogel (HAPPF) Coordinated Regeneration for High‐Quality Diabetic Wound Repair.A self‐regulating dynamic hydrogel is developed to deliver a fluorogenic H2S donor in response to excessive ROS. Released H2S acts as a master regulator to resolve chronic inflammation (M2 polarization), restore VEGF‐driven angiogenesis, and rebalance ...
Xuyang Ning +7 more
wiley +1 more source
Journal of Innovative Optical Health SciencesTime-resolved flow cytometry (TRFC) was used to measure metabolic differences in estrogen receptor-positive breast cancer cells. This specialty cytometry technique measures fluorescence lifetimes as a single-cell parameter thereby providing a unique ...
Samantha Valentino +3 more
doaj +1 more source
Advanced Science, EarlyView.A minimally invasive optical window enables stable, long‐term imaging of peripheral nerves in vivo at single‐axon resolution. Dynamic processes of degeneration, regeneration, and cellular remodeling are visualized across multiple time scales within the same nerve region, providing a unique platform to study a variety of anatomical and molecular events ...
Igor D. Luzhansky +15 more
wiley +1 more source
Advanced Science, EarlyView.Cartilage injury promotes local fibrinogen deposition, which accelerates monosodium urate crystallization and activates integrin‐mediated matrix‐degradation. This self‐amplifying cycle drives gout‐related cartilage erosion. Disrupting fibrinogen deposition or restoring the cartilage barrier could interrupt this vicious cycle.
Hanlin Xu +7 more
wiley +1 more source
Autofluorescence bronchoscopy in lung transplantation [PDF]
, 2015 Despite little is known about airway perfusion in the early period after lung transplantation, central bronchial stenosis is attributed to pour vascularization.
V. Rossetti +5 more
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Advanced Science, EarlyView.Through integrated proteomic and metabolomic profiling, Zhao et al. identified three molecular subtypes of high‐grade serous ovarian cancer. The high‐risk subtype exhibits activated arachidonic acid metabolism and cyclooxygenase‐2 overexpression. This metabolic axis promotes M2‐like macrophage infiltration, which contributes to platinum resistance ...
Yuxi Zhao +11 more
wiley +1 more source