Results 51 to 60 of about 1,124,846 (342)

Recombinant human PDCD5 (rhPDCD5) protein is protective in a mouse model of multiple sclerosis. [PDF]

, 2015
BackgroundIn multiple sclerosis (MS) and its widely used animal model, experimental autoimmune encephalomyelitis (EAE), autoreactive T cells contribute importantly to central nervous system (CNS) tissue damage and disease progression. Promoting apoptosis
Chen, Yingyu, Deng, Wenbin, Liu, Wenwei, Xiao, Juan   +3 more
core   +2 more sources

Hydroxychloroquine in patients with systemic lupus erythematosus: how much is enough?

Lupus Science and Medicine
Objective To assess the daily and weight-adjusted dosages of hydroxychloroquine (HCQ) and the effects on long-term remission in the Lupus-Cruces cohort.Methods Observational study of routine clinical care data. We selected inception patients treated with
Guillermo Ruiz-Irastorza, Daniel Martín-Iglesias, Ioana Ruiz-Arruza, Fernando Arizpe, Victor Moreno-Torres, Diana Paredes-Ruiz, Valerio Campos-Rodriguez, Laura Amo   +7 more
doaj   +1 more source

Autoimmune Bullous Disease Quality of Life (ABQoL) questionnaire: Validation of the translated Persian version in pemphigus vulgaris

International Journal of Women's Dermatology, 2020
Background: Autoimmune bullous diseases are a group of rare, chronic, blistering diseases, with pemphigus vulgaris (PV) being the most common type in Iran.
Amir Teimourpour, PhD, Kowsar Hedayat, MD, Fereshteh Salarvand, MD, Narges Ghandi, MD, Maryam Ghiasi, MD, Hamidreza Mahmoudi, MD, Kamran Balighi, MD, Roja Toosi, MD, MPH, Farnam Mohebi, MD, MPH, Ali Nili, MD, Maryam Daneshpazhooh, MD, Dedee F. Murrell, MA, BMBCh, MD, FACD, Cheyda Chams-Davatchi, MD   +12 more
doaj   +1 more source

Alopecia areata: a multifactorial autoimmune condition [PDF]

, 2019
Alopecia areata is an autoimmune disease that results in non-scarring hair loss, and it is clinically characterised by small patches of baldness on the scalp and/or around the body. It can later progress to total loss of scalp hair (Alopecia totalis) and/
Butcher, John P., Henriquez, Fiona L., Reid, Stuart, Simakou, Teontor   +3 more
core   +1 more source

A Comparative Study of Demographic and Clinical Criteria Between Male and Female Patients With Pemphigus Referred to a Referral Hospital in Iran

Dermatology Research and Practice
Conclusion: The study highlights significant gender differences in the presentation and severity of pemphigus, underscoring the importance of gender-specific approaches in the diagnosis and management of this condition.
Zeinab Aryanian, Kamran Balighi, Nafiseh Esmaeli, Maryam Daneshpazhooh, Nasim Mazloomi Tootoonchi, Zahra Razavi, Fereshteh Beigmohammadi, Umamah Gul, Azadeh Khayyat, Parvaneh Hatami   +9 more
doaj   +1 more source

Cytokine and autoantibody clusters interaction in systemic lupus erythematosus

Journal of Translational Medicine, 2017
Background Evidence supports the existence of different subphenotypes in systemic lupus erythematosus (SLE) and the pivotal role of cytokines and autoantibodies, which interact in a highly complex network.
Yovana Pacheco, Julián Barahona-Correa, Diana M. Monsalve, Yeny Acosta-Ampudia, Manuel Rojas, Yhojan Rodríguez, Juliana Saavedra, Mónica Rodríguez-Jiménez, Rubén D. Mantilla, Carolina Ramírez-Santana, Nicolás Molano-González, Juan-Manuel Anaya   +11 more
doaj   +1 more source

Integrating spatial transcriptomics with single-cell transcriptomics reveals a spatiotemporal gene landscape of the human developing kidney

Cell & Bioscience, 2022
Background Research on spatiotemporal gene landscape can provide insights into the spatial characteristics of human kidney development and facilitate kidney organoid cultivation.
Hongwei Wu, Fanna Liu, Yu Shangguan, Yane Yang, Wei Shi, Wenlong Hu, Zhipeng Zeng, Nan Hu, Xinzhou Zhang, Berthold Hocher, Donge Tang, Lianghong Yin, Yong Dai   +12 more
doaj   +1 more source

Vitiligo and autoimmune thyroid disorders [PDF]

, 2017
Vitiligo represents the most common cause of acquired skin, hair and oral depigmentation, affecting 0.5-1% of the population worldwide. It is clinically characterized by the appearance of disfiguring circumscribed skin macules following melanocyte ...
Baldini, Enke, Carbotta, Giovanni, Catania, Antonio, D'Armiento, Eleonora, Odorisio, Teresa, Persechino, Severino, Pironi, Daniele, Rendina, Roberta, Sorrenti, Salvatore, Tartaglia, Francesco, Ulisse, Salvatore   +10 more
core   +2 more sources

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Thrombosis and Hyperinflammation in COVID-19 Acute Phase Are Related to Anti-Phosphatidylserine and Anti-Phosphatidylinositol Antibody Positivity

Biomedicines, 2023
Antiphospholipid antibodies (APLA) are strongly associated with thrombosis seen in patients with antiphospholipid syndrome. In COVID-19, thrombosis has been observed as one of the main comorbidities.
Jaume Alijotas-Reig, Ariadna Anunciación-Llunell, Stephanie Morales-Pérez, Jaume Trapé, Enrique Esteve-Valverde, Francesc Miro-Mur   +5 more
doaj   +1 more source