Results 41 to 50 of about 904 (147)

Post‐Tuberculosis Adrenal Crisis in a Young Boy: A Case Report

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT An adrenal crisis should be considered in children with a history of tuberculosis who present with shock, hypoglycemia, and hyperpigmentation. Even years after successful treatment, TB can cause irreversible adrenal damage leading to primary adrenal insufficiency. Early recognition and prompt glucocorticoid replacement are lifesaving.
Aisha Haleem, Saad Ashraf, Daniya Tarique, Muhammad Zohair, Ajeet Singh, Biruk Demisse Ayalew   +5 more
wiley   +1 more source

Glucocorticoids‐Induced Adrenal Insufficiency With Intractable Vomiting: A Case Report

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT An 80‐year‐old male patient was admitted to our hospital with a one‐year history of recurrent reflux and vomiting, accompanied by mild fatigue and decreased appetite. Despite initial treatment with prokinetic agents, his symptoms showed minimal improvement.
Yamei Ran, Yongmei Peng, Juan Xiao, Li Zhang, Kangqi Wu, Wenjing Sun   +5 more
wiley   +1 more source

CXCL10 Promotes Spinal Macrophage Recruitment via the JAK/STAT3 Pathway to Induce Pain in Experimental Autoimmune Prostatitis

Cell Proliferation, Volume 58, Issue 4, April 2025.
The CXCL10/CXCR3 axis was involved in spinal macrophage infiltration through activating the JAK/STAT3 pathway. The prostate NGF/TrKA axis was involved in the neuroinflammation and pain in chronic prostatitis, and inhibition of NGF could attenuate pain response in chronic prostatitis, which provided novel therapeutic targets for pain treatment in ...
Lei Chen, Ziqi Chen, Jia Chen, Hexi Du, Xianguo Chen, Jing Chen, Hui Wang, Chaozhao Liang   +7 more
wiley   +1 more source

Longitudinal assessment of thyroid function in dogs with hypoadrenocorticism: Clinical outcomes and prevalence of autoantibodies

Journal of Veterinary Internal Medicine, Volume 39, Issue 1, January/February 2025.
Abstract Background Knowledge about primary hypoadrenocorticism coexisting with immune‐mediated thyroiditis (Schmidt's syndrome) in dogs is limited. Objective To evaluate thyroid function in dogs with naturally occurring hypoadrenocorticism before and during treatment. Animals Sixty‐six client‐owned dogs.
Nadja S. Sieber‐Ruckstuhl, Barbara Riond, Federico Fracassi, Claudia Kuemmerle‐Fraune, Solène Meunier, Regina Hofmann‐Lehmann, Claudia E. Reusch, Claudia Mueller, Natalie Hofer‐Inteeworn, Felicitas S. Boretti   +9 more
wiley   +1 more source

Clinical findings, treatment, and outcomes in cats with naturally occurring hypoadrenocorticism: 41 cases

Journal of Veterinary Internal Medicine, Volume 39, Issue 1, January/February 2025.
Abstract Background Hypoadrenocorticism in cats is uncommonly reported. Most reports consist of cats with hyponatremia, hyperkalemia, or both. Hypothesis/Objectives To describe clinical findings, treatment response, and outcome in cats diagnosed with hypoadrenocorticism, including cats with abnormal and normal serum sodium and potassium concentrations.
Emma Roberts, Ian K. Ramsey, Ruth Gostelow, Anna Latysheva, Luca Battaglia, Paolo Silvestrini, Ghita Benchekroun, Karen Brenner, Bérénice Conversy, Riccardo Ferriani, Andre Kortum, Lisa Stammeleer, Nele Van den Steen, Flavia Tavares, Julia Lieser, Angie Hibbert, Antoine Duclos, Troy Bunn, Alisdair M Boag, Carolina Arenas, Kirsty Roe, Florian K. Zeugswetter, Yi Cui, Imogen Schofield, Federico Fracassi   +24 more
wiley   +1 more source

Adrenal insufficiency induced by immune checkpoint inhibitors anticancer therapy

Nowotwory
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment and significantly improved the prognosisof patients with advanced tumors.
Paulina Ramaneckaite, Zuzanna Ratuszna, Julia Brymora, Ewa Zalewska, Renata Stodulska-Świątkowska   +4 more
doaj   +1 more source

Repurposing of rituximab biosimilars to treat B cell mediated autoimmune diseases

The FASEB Journal, Volume 38, Issue 5, 15 March 2024.
B cell functions include: (A) acting as antigen‐presenting cells (APCs) through B‐cell antigen receptors (BCRs), (B) interacting with T cells via the major histocompatibility complex class II (MHC II) and T‐cell receptors (TCRs), (C) producing autoantibodies, and (D) producing inflammatory cytokines.
Agata Mostkowska, Guy Rousseau, Noël J‐M Raynal   +2 more
wiley   +1 more source

Primary adrenal insufficiency: case study IN 5 tertiary hospitals

Anales de Pediatría (English Edition)
Introduction: Primary adrenal insufficiency (PAI) in children is a rare condition characterized by deficient production of glucocorticoids and/or mineralocorticoids. The clinical manifestations are nonspecific and insidious.
María Teresa Ovejero García, Blanca Sáez Gallego, Ana Coral Barreda Bonís, Jesús Domínguez Riscart, María Beatriz Garnier Rodríguez, Ruth Molina Suárez, Antonio De Arriba Muñoz   +6 more
doaj   +1 more source

Pathogenesis of acute adrenal crisis in children: current concepts and emerging mechanisms

Фундаментальная и клиническая медицина
Aim. The aim of this article is to provide a comprehensive review of the pathogenetic mechanisms underlying the development of acute adrenal crisis (AAC) in children, with an emphasis on recent experimental and clinical findings. Materials and Methods. A
Yu. V. Bykov
doaj   +1 more source

GDF15 in Patients with Autoimmune Primary Adrenal Insufficiency

International Journal of Molecular Sciences
Growth differentiation factor 15 (GDF15) is a stress-response protein that conveys cellular distress signals to the brain and activates neural pathways leading to weight loss. GDF15 levels are increased in glucocorticoid deficiency; however, multiple factors may influence its levels in patients with primary adrenal insufficiency (PAI). The objective of
Aleksandra Zdrojowy-Wełna, Jowita Halupczok-Żyła, Katarzyna Kolačkov, Justyna Kuliczkowska-Płaksej, Aleksandra Jawiarczyk-Przybyłowska, Barbara Stachowska, Iga Zendran-Zahorska, Marek Bolanowski   +7 more
openaire   +2 more sources