Results 41 to 50 of about 224,710 (181)
Clinical Case Reports, Volume 14, Issue 4, April 2026.Immune checkpoint inhibitors (ICIs) can cause immune‐related adverse events (irAEs), including hypophysitis—particularly with CTLA‐4 inhibitors. Atypical presentations in older patients may mimic cancer‐related fatigue or treatment side effects, delaying diagnosis.
Nadia Grace Obaed +5 more
wiley +1 more source
The Diagnosis and Staging of Hypocortisolism in Progressing Autoimmune Adrenalitis [PDF]
Pediatric Research, 1983 The course of development of hypocortisolism was studied in 20 patients with autoimmune polyendocrinopathy-candidosis-ectodermal dystrophy (APECED) for 1.3-9.3 years during which time the patients underwent at least three 2-h ACTH tests (2hAT). A slow progression of the disease was evident and could be staged.
S, Leisti, P, Ahonen, J, Perheentupa
openaire +2 more sources
The CYP2D6 animal model: how to induce autoimmune hepatitis in mice [PDF]
, 2012 Autoimmune hepatitis is a rare but life threatening autoimmune disease of the liver of unknown etiology1,2. In the past many attempts have been made to generate an animal model that reflects the characteristics of the human disease 3-5.
Christen, Urs +2 more
core +1 more source
Presentation and Management of Addison's Disease in a 10‐Year‐Old Boy: A Case Report
iLABMED, Volume 4, Issue 1, Page 59-63, March 2026.ABSTRACT Addison's disease, or primary adrenal insufficiency, is a rare endocrine disorder characterized by impaired adrenal hormone production. We report a case of a 10‐year‐old boy with congenital adrenal hyperplasia and secondary Addison's disease on long‐term corticosteroid therapy who presented with recurrent non‐bilious vomiting, low‐grade fever,
Srinivasan Sivannan +4 more
wiley +1 more source
Peptide-based immunotherapy of experimental autoimmune encephalomyelitis without anaphylaxis [PDF]
, 2007 Administration of peptide antigens in tolerogenic form holds promise as a specific treatment for autoimmune and allergic disorders. However, experiments in rodent autoimmune models have highlighted the risk of anaphylaxis in response to systemic peptide ...
Stephen M. Anderton +7 more
core +1 more source
Expert Perspective: Diagnosis and Treatment of Castleman Disease
Arthritis &Rheumatology, Volume 78, Issue 1, Page 12-25, January 2026.Castleman disease (CD) is a major diagnostic challenge for rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region, whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y. C. Chen +2 more
wiley +1 more source
Rat models of autoimmune uveitis [PDF]
, 2008 Experimental autoimmune uveitis ( EAU) in Lewis rats is a well-established model for human uveitis. During the last years we used this model to demonstrate extraocular induction of uveitis by antigenic mimicry of environmental antigens with retinal ...
Wildner, Gerhild +2 more
core +1 more source
Diagnosis and treatment of endocrinological complications of immunotherapy of oncological diseases
Ожирение и метаболизм, 2018 In this lecture, we discuss in detail the endocrinopathies associated with the use of immune-checkpoint inhibitors in oncology. The cases, terms and features of clinical manifestations of endocrine-related immune reactions are discussed, and practical ...
Ekaterina A. Pigarova +3 more
doaj +1 more source
International Journal of Clinical Practice, Volume 2026, Issue 1, 2026.Background Primary adrenal insufficiency (PAI) is a rare but life‐threatening endocrine disorder with diverse etiologies. Although research activity has expanded in recent decades, a comprehensive bibliometric analysis of global PAI scholarship has been lacking.
Dianmei Xi +4 more
wiley +1 more source
PAS the Salt: A Case of Autoimmune Polyglandular Syndrome Type II [PDF]
, 2021 CASE DESCRIPTION: Here we present the case of a 71 year old female with a decades-long history of Hashimoto thyroiditis and vitiligo who developed Addison Disease (AD).
d'Arnaud, Lindsey +3 more
core +1 more source