Results 21 to 30 of about 904 (147)

Characteristics and Challenges of Primary Adrenal Insufficiency in Africa: A Review of the Literature

International Journal of Endocrinology, Volume 2022, Issue 1, 2022., 2022
Backgrounds. Africa comprises 54 countries with varying degrees of economic development. As with other healthcare systems, rare diseases such as adrenal insufficiency are neglected and poorly documented. Objectives. We wished to explore primary adrenal insufficiency (PAI) in Africa, its prevalence, aetiology, genetics, presentation, diagnosis, and ...
Thabiso R. P. Mofokeng, Salem A. Beshyah, Ian L. Ross, Giuseppe Reimondo   +3 more
wiley   +1 more source

Expert Perspective: Diagnosis and Treatment of Castleman Disease. [PDF]

Arthritis Rheumatol
Castleman disease (CD) is a major diagnostic challenge for rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region, whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Chen LYC, Zhang L, Fajgenbaum DC.
europepmc   +2 more sources

Long‐term corticosteroid use, adrenal insufficiency and the need for steroid‐sparing treatment in adult severe asthma

Journal of Internal Medicine, Volume 290, Issue 2, Page 240-256, August 2021., 2021
Abstract Secondary adrenal insufficiency (AI) occurs as the result of any process that disrupts normal hypothalamic and/or anterior pituitary function and causes a decrease in the secretion of steroid hormones from the adrenal cortex. The most common cause of secondary AI is exogenous corticosteroid therapy administered at supraphysiologic dosages for ≥
M. Gurnell, L. G. Heaney, D. Price, A. Menzies‐Gow   +3 more
wiley   +1 more source

Challenging Diagnosis of Addison’s Disease Presenting with Adrenal Crisis

Case Reports in Endocrinology, Volume 2021, Issue 1, 2021., 2021
Primary adrenal insufficiency, also known as Addison’s disease, is a rare but potentially fatal condition resulting from the failure of the adrenal cortex to produce glucocorticoid and/or mineralocorticoid hormones. Unfortunately, the clinical manifestation of primary adrenal insufficiency is not specific and often progresses insidiously, resulting in ...
Ni Wayan Wina Dharmesti, Made Ratna Saraswati, Ketut Suastika, Wira Gotera, I Made Pande Dwipayana, Toshihiro Kita   +5 more
wiley   +1 more source

Adrenal crisis in a 14-year-old boy 12  years after hematopoietic stem cell transplantation

Endocrinology, Diabetes & Metabolism Case Reports, 2018
We report on a boy of Albanian descent with the history of juvenile myelomonocytic leukemia (JMML). JMML was diagnosed at the age of 17 months and treated by hematopoietic stem cell transplantation (HSCT).
Theresa Penger, Andrea Albrecht, Michaela Marx, Daniel Stachel, Markus Metzler, Helmuth G Dörr   +5 more
doaj   +1 more source

Pediatric Primary Adrenal Insufficiency: A 21-year Single Center Experience

JCRPE, 2021
Objective:Primary adrenal insufficiency (PAI) is a rare but potentially life-threatening condition. In childhood, PAI is usually caused by monogenic diseases.
Emine Çamtosun, İsmail Dündar, Ayşehan Akıncı, Leman Kayaş, Nurdan Çiftçi   +4 more
doaj   +1 more source

Adrenal Crisis and Autoimmune Polyglandular Syndromes [PDF]

Baylor University Medical Center Proceedings, 2017
We report a 67-year-old woman who presented with adrenal crisis as a manifestation of autoimmune polyglandular syndrome 2, a polygenic disorder characterized by concurrent primary adrenal insufficiency and either autoimmune thyroid disease or type 1 diabetes mellitus.
Zachary K, Freeland, Richard, Lueking, Ginger, Tsai-Nguyen, Thoris, Pan, Adan, Mora   +4 more
openaire   +2 more sources

Acute Heart Failure as a First Manifestation of Primary Adrenal Insufficiency: Highly Lethal If Not Diagnosed! [PDF]

Case Rep Endocrinol
Background. Primary adrenal insufficiency is an uncommon condition that manifests as nonspecific symptoms such as fatigue, weight loss, salt craving, and hyperpigmentation. Common cardiovascular presentations of AI are hypotension, arrhythmias, and syncope. However, acute heart failure is an uncommon presentation. Case Presentation. Here, a 26‐year‐old
Heidarpour M, Zare MM, Armani S, Torkashvan H, Mazaheri-Tehrani S, Shafie D.   +5 more
europepmc   +2 more sources

Coexistence of Congenital Adrenal Hyperplasia and Autoimmune Addison's Disease

Frontiers in Endocrinology, 2019
Background: Underlying causes of adrenal insufficiency include congenital adrenal hyperplasia (CAH) and autoimmune adrenocortical destruction leading to autoimmune Addison's disease (AAD). Here, we report a patient with a homozygous stop-gain mutation in
Sigrid Aslaksen, Sigrid Aslaksen, Paal Methlie, Paal Methlie, Paal Methlie, Magnus D. Vigeland, Magnus D. Vigeland, Dag E. Jøssang, Anette B. Wolff, Anette B. Wolff, Ying Sheng, Bergithe E. Oftedal, Bergithe E. Oftedal, Beate Skinningsrud, Dag E. Undlien, Dag E. Undlien, Kaja K. Selmer, Kaja K. Selmer, Eystein S. Husebye, Eystein S. Husebye, Eystein S. Husebye, Eirik Bratland, Eirik Bratland   +22 more
doaj   +1 more source

Parkinsonism as a Rare Manifestation of Hashimoto Encephalopathy Associated with Autoimmune Polyendocrine Syndrome: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Hashimoto’s encephalopathy is a rare manifestation of a common autoimmune disease, characterised classically by its association with autoimmune thyroid disease and responsiveness to steroids. Usual clinical manifestations include a relapsing-remitting
Diksha Samsukha, Rohidas T Borse, Meenal Chandanwale   +2 more
doaj   +1 more source