Results 11 to 20 of about 224,710 (181)

A variant in RESF1 is associated with Addison’s disease and multiple autoimmune syndrome in young Nova Scotia Duck Tolling Retrievers [PDF]

Scientific Reports
Addison’s disease (AD) results in glucocorticoid and mineralocorticoid deficiencies and is often immune-mediated. While AD is uncommon in dogs, Nova Scotia Duck Tolling Retrievers (NSDTRs) exhibit increased incidence, suggesting genetic predisposition ...
Emily Brown, Scarlett Varney, Amy Young, Zena Wolf, Oded Foreman, Claire M. Wade, Angela Hughes, Anita Oberbauer, Noa Safra, Kerstin Lindblad-Toh, Shelley Burton, Danika Bannasch   +11 more
doaj   +3 more sources

Sub-clinical Addison′s disease

Indian Journal of Endocrinology and Metabolism, 2012
As autoimmune adrenalitis is fast replacing tuberculosis as the most common etiology cause of adrenal insufficiency, subtler forms of the same are being recognised as subclinical addison′s disease.
Manash P Baruah
doaj   +2 more sources

Adrenal Tuberculosis Presenting as Adrenal Crisis: A Rare Presentation of Common Disease. [PDF]

Case Rep Endocrinol
We report a case of a 45‐year‐old man presenting with hypotension, hyponatremia, hyperkalemia, hypoglycemia and diffuse hyperpigmentation. Monitoring serum cortisol was 0.5 μg/dL, and the computerized tomography (CT) scan showed bilateral adrenal enlargement, consistent with primarily adrenal insufficiency (AI) likely due to adrenal tuberculosis (TB ...
Fenta BK, Yihdego AS, Kurtaile BK, Ketema W.   +3 more
europepmc   +2 more sources

IFN-γ-producing self-reactive CD4+ T cells induce autoimmune adrenalitis in a mouse model of Addison's disease. [PDF]

JCI Insight
Autoimmune Addison’s disease (AD) is a rare but life-threatening disorder caused by immune-mediated destruction of the adrenal cortex, and progress in therapy has been limited by insufficient mechanistic insight. Here, we establish a
Andreyeva A, Michalik J, Niederlova V, Cimermanova V, Drobek A, Sedlacek R, Prochazka J, Labaj J, Fedosieieva O, Kanczkowski W, Draber P, Sulen A, Stepanek O, Neuwirth A.   +13 more
europepmc   +2 more sources

Parkinsonism as a Rare Manifestation of Hashimoto Encephalopathy Associated with Autoimmune Polyendocrine Syndrome: A Case Report [PDF]

Journal of Clinical and Diagnostic Research
Hashimoto’s encephalopathy is a rare manifestation of a common autoimmune disease, characterised classically by its association with autoimmune thyroid disease and responsiveness to steroids. Usual clinical manifestations include a relapsing-remitting
Diksha Samsukha, Rohidas T Borse, Meenal Chandanwale   +2 more
doaj   +2 more sources

Coexistence of Congenital Adrenal Hyperplasia and Autoimmune Addison's Disease [PDF]

Frontiers in Endocrinology, 2019
Background: Underlying causes of adrenal insufficiency include congenital adrenal hyperplasia (CAH) and autoimmune adrenocortical destruction leading to autoimmune Addison's disease (AAD). Here, we report a patient with a homozygous stop-gain mutation in
Sigrid Aslaksen, Sigrid Aslaksen, Paal Methlie, Paal Methlie, Paal Methlie, Magnus D. Vigeland, Magnus D. Vigeland, Dag E. Jøssang, Anette B. Wolff, Anette B. Wolff, Ying Sheng, Bergithe E. Oftedal, Bergithe E. Oftedal, Beate Skinningsrud, Dag E. Undlien, Dag E. Undlien, Kaja K. Selmer, Kaja K. Selmer, Eystein S. Husebye, Eystein S. Husebye, Eystein S. Husebye, Eirik Bratland, Eirik Bratland   +22 more
doaj   +2 more sources

Adrenal Insufficiency due to Disseminated <i>Cryptococcus</i> in an Immunocompetent Individual. [PDF]

Case Rep Endocrinol
Primary adrenal insufficiency due to infiltrative fungal infections, such as Cryptococcus neoformans, is rare, particularly in immunocompetent patients. We present a case of an immunocompetent 61‐year‐old man who presented with bilateral adrenal enlargement and adrenal insufficiency, with a 3‐month history of generalised fatigue, weight loss and ...
Knott JA, Apostoloski Z.
europepmc   +2 more sources

Adrenal crisis in a 14-year-old boy 12  years after hematopoietic stem cell transplantation

Endocrinology, Diabetes & Metabolism Case Reports, 2018
We report on a boy of Albanian descent with the history of juvenile myelomonocytic leukemia (JMML). JMML was diagnosed at the age of 17 months and treated by hematopoietic stem cell transplantation (HSCT).
Theresa Penger, Andrea Albrecht, Michaela Marx, Daniel Stachel, Markus Metzler, Helmuth G Dörr   +5 more
doaj   +2 more sources

Acute Mania in a Patient With Primary Adrenal Insufficiency Due to Autoimmune Adrenalitis: A Case Report [PDF]

, 2023
We describe a rare case of acute mania in the setting of autoimmune adrenalitis. A 41-year-old male with no previous psychiatric diagnoses presented with impulsivity, grandiosity, delusions of telepathy, and hyperreligiosity following a previous ...
Alex Wang, Gabriel, Chris, John Luo, Nolan J. Brown, Reza Farokhpay, Chris Gabriel, Wang, Alex, Farokhpay, Reza, Brown, Nolan J, Gianna Fote, Fote, Gianna, Luo, John   +11 more
core   +1 more source

In vivo application of recombinant interleukin 2 in the immunotherapy of established cytomegalovirus infection [PDF]

, 1987
We have shown in a murine model system for cytomegalovirus (CMV) disease in the immunocompromised host that in vivo application of recombinant human IL-2 (rhIL-2) can enhance the antiviral effect of a limited number of CD8+T lymphocytes, not only in ...
Reddehase, Matthias J., W Mutter, Koszinowski, Ulrich H., Wolfgang Mutter, J. Reddehase, M J Reddehase, U H Koszinowski, Koszinowski, Ulrich, Mutter, Wolfgang, Ulrich H. Koszinowski   +9 more
core   +2 more sources