Results 121 to 130 of about 9,492,165 (393)

Are autoimmune diseases predictable?

open access: yesAutoimmunity Reviews, 2012
Autoimmune diseases are complex diseases resulting of the interaction between both genetics and environmental factors over time. Different phases in the development of autoimmune diseases are characterized by the detection of serum autoantibodies several months or years before the onset of clinical manifestations and subsequent diagnosis.
Tobón, Gabriel J   +5 more
openaire   +7 more sources

CSF Tau Is a Biomarker of Hippocampal Injury in Cryptogenic New‐Onset Refractory Status Epilepticus

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cryptogenic new‐onset refractory status epilepticus (cNORSE) is a devastating condition characterized by the de novo onset of status epilepticus with unclear etiology. The identification of relevant early biomarkers in cNORSE is important to elucidate pathophysiology, aid clinical decision‐making, and prognosticate outcomes in cNORSE.
Yihui Goh   +8 more
wiley   +1 more source

Prediction of Alzheimer's disease-associated genes by integration of GWAS summary data and expression data [PDF]

open access: yesarXiv, 2018
Alzheimer's disease is the most common cause of dementia. It is the fifth-leading cause of death among elderly people. With high genetic heritability (79%), finding disease causal genes is a crucial step in find treatment for AD. Following the International Genomics of Alzheimer's Project (IGAP), many disease-associated genes have been identified ...
arxiv  

Outbreak of autoimmune disease in silicosis linked to artificial stone.

open access: yesOccupational Medicine, 2015
BACKGROUND There is a well-established association between inhalational exposure to silica and autoimmune disease. We recently observed an outbreak of silica-related autoimmune disease among synthetic stone construction workers with silicosis referred ...
O. Shtraichman   +6 more
semanticscholar   +1 more source

ADAPT NXT: Fixed Cycles or Every‐Other‐Week IV Efgartigimod in Generalized Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This phase 3b, open‐label, randomized ADAPT NXT study investigated the efficacy, safety, and tolerability of efgartigimod administered in either a fixed cycles dosing regimen (3 cycles of 4 once‐weekly infusions, with 4 weeks between cycles) or a cycle followed by every‐other‐week (Q2W) dosing.
Ali A. Habib   +16 more
wiley   +1 more source

Inflammatory Bowel Disease and the Risk of Autoimmune Diseases.

open access: yesJournal of Crohn's & Colitis, 2016
BACKGROUND An increased risk of autoimmune disease has been reported in patients with inflammatory bowel disease [IBD]. Using data from the Clinical Practice Research Datalink [CPRD], this study set out to further examine this relationship.
J. Claire Wilson   +3 more
semanticscholar   +1 more source

National Institute of Health and Care Excellence Clinical Criteria for the Diagnosis of Knee Osteoarthritis: A Prospective Diagnostic Accuracy Study in Individuals With Type 2 Diabetes

open access: yesArthritis Care &Research, EarlyView.
Objective The National Institute of Health and Care Excellence (NICE) criteria for osteoarthritis (OA) obviate the need for physical examination or imaging, and their use may improve timely diagnosis of OA. However, they have not been validated. Methods Within a larger study of individuals with type 2 diabetes, participants with and without self ...
Lauren K. King   +6 more
wiley   +1 more source

T-cell metabolism in autoimmune disease

open access: yesArthritis Research & Therapy, 2015
Cancer cells have long been known to fuel their pathogenic growth habits by sustaining a high glycolytic flux, first described almost 90 years ago as the so-called Warburg effect.
Zhen Yang   +3 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy