Results 171 to 180 of about 865,910 (294)

Bioprinted Constructs in the Regulatory Landscape: Current State and Future Perspectives

Advanced Materials, EarlyView.
Bioprinting has rapidly emerged as a transformative technology in biomedical research, offering unprecedented potential to replicate complex tissues. Despite its promise, clinical translation remains limited due to regulatory hurdles. This review explores global regulatory frameworks, comparing approaches in the EU, U.S., China, and Australia, and ...
Francesca Perin, Liliang Ouyang, Khoon S. Lim, Antonella Motta, Devid Maniglio, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Th17 cell pathogenicity in autoimmune disease. [PDF]

Exp Mol Med
Park E, Ciofani M.
europepmc   +1 more source

G-protein signaling modulator-3, a gene linked to autoimmune diseases, regulates monocyte function and its deficiency protects from inflammatory arthritis

, 2012
Patrick M. Giguère, Matthew J. Billard, Geneviève Laroche, Brian K. Buckley, Roman G. Timoshchenko, Marcus W. McGinnis, Denise Esserman, Oded Foreman, Peng Liu, David P. Siderovski, Teresa K. Tarrant   +10 more
openalex   +1 more source

Therapeutic Antibodies for Mosquito‐Borne Orthoflavivirus Infections: Discovery, Engineering Approaches, and Advances in mRNA‐Based Delivery Systems

Advanced Therapeutics, EarlyView.
This review explores how antibody engineering and display technologies are driving therapeutic advances against mosquito‐borne orthoflaviviruses such as Zika, dengue, and yellow fever viruses. It highlights diverse neutralizing targets on the envelope protein, including the conserved fusion loop, and discusses how Fc engineering, rational antigen ...
Ana Clara Barbosa Antonelli, Lucas Silva Rodrigues, Maria Clara Moura Pinheiro, Sylvia Barbosa Pinhate, Marcelo de Macedo Brígido, Andréa Queiroz Maranhão   +5 more
wiley   +1 more source

Co-occurrence of Protein Crotonylation and 2‑Hydroxyisobutyrylation in the Proteome of End-Stage Renal Disease

ACS Omega, 2021
Jingjing Dong, Yixi Li, Fengping Zheng, Wenbiao Chen, Shaoying Huang, Xianqing Zhou, Kang Wang, Wanxia Cai, HaiPing Liu, Lianghong Yin, Qiang Li, Donge Tang, Yong Dai   +12 more
doaj   +1 more source

Association of Individual or Family History of Autoimmune Disease With Future Development of Type 1 Diabetes. [PDF]

Diabetes Metab Res Rev
Thomas N, Vaidya B, Leslie RD, Agardh D, Oram R, Dabelea D, Singh A, Chantzichristos D, Rewers M.   +8 more
europepmc   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

Transglutaminase 2 and Ferroptosis: a new liaison?

Cell Death Discovery, 2023
Mara Gagliardi, Valentina Saverio, Federica Rossin, Manuela D’Eletto, Marco Corazzari   +4 more
doaj   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

Advances and prospects of CAR-T cell therapy in autoimmune disease treatment. [PDF]

Medicine (Baltimore)
Wang T, Fu T, Xing G, Cai H, Tong Y.
europepmc   +1 more source