Results 211 to 220 of about 865,910 (294)

STAT3 S727 phosphorylation drives pathogenic Th17 differentiation and neuroinflammation in autoimmune disease. [PDF]

J Neuroinflammation
Prado DS, Kutuva AR, Cattley RT, Sonego AB, Sutariya P, Im E, Wu S, Lee M, Cumberland RL, Mehta I, Delgoffe GM, Boggess WC, Faeder JR, Shlomchik MJ, Hawse WF.   +14 more
europepmc   +1 more source

Assessment of autoimmune rheumatic diseases activity during pregnancy [PDF]

Mai Omar Abdelaziz, Mohamed Ismail Abdelakareem, Mahmoud Soliman Mawad, Eman Ragab Abdelradi   +3 more
openalex   +1 more source

Secondary Necrosis Following Caspase‐Activation can Occur Independently of Gasdermin E

Advanced Science, EarlyView.
Secondary necrosis follows apoptosis, but its mechanism is unclear. This study shows that although gasdermin E is cleaved during this process, it is not required for membrane rupture. Across multiple models, secondary necrosis occurred regardless of gasdermin E presence, challenging prior claims and redefining the understanding of how apoptotic cells ...
Shubhangi Gavali, Francesca Maremonti, Wulf Tonnus, Florian Gembardt, Marlena Nastassja Schlecht, Karolin Flade, Anne von Mässenhausen, Stephen W. G. Tait, Stefan R. Bornstein, Andreas Linkermann   +9 more
wiley   +1 more source

Köbner Phenomenon in a Rituximab-Treated Pemphigus Patient: Beware Disease Activity

Dermatology Practical & Conceptual, 2019
Soheil Tavakolpour, Hamidreza Mahmoudi, Nika Kianfar, Shayan Dasdar, Maryam Daneshpazhooh   +4 more
doaj   +1 more source

Human TIM-3-CD22 interaction regulates innate immune activation in autoimmune diseases 4325 [PDF]

Tomokazu S Sumida, Alice Yi
openalex   +1 more source

Integrating Single‐Cell Transcriptome‐Wide Mendelian Randomization and Differentially Expressed Gene Analyses to Prioritize Dynamic Immune‐Related Drug Targets for Cancers

Advanced Science, EarlyView.
Inspired by evidence triangulation, a new sensitivity method called MR‐DEG is developed, which uses the differentially expressed gene (DEG) results as additional evidence to minimize pleiotropic effects and strengthen Mendelian randomization (MR) causal estimates. Using dynamic single‐cell expression quantitative trait loci (eQTLs) as an example, it is
Jie Zheng, Qian Yang, Haoyu Liu, Huiling Zhao, Shuangyuan Wang, Yi Liu, Xueyan Wu, Yilan Ding, Hui Ying, Youqiu Ye, Xi Huang, Lei Ye, Ruizhi Zheng, Hong Lin, Mian Li, Tiange Wang, Zhiyun Zhao, Min Xu, Yi Duan, Hao Guo, Zhongshang Yuan, Philip Haycock, George Davey Smith, Richard M Martin, Guang Ning, Fang Hu, Weiqing Wang, Tom R. Gaunt, Jieli Lu, Yufang Bi   +29 more
wiley   +1 more source

Immune Organoids: A Review of Their Applications in Cancer and Autoimmune Disease Immunotherapy. [PDF]

Curr Issues Mol Biol
Olawade DB, Oisakede EO, Egbon E, Ovsepian SV, Boussios S.   +4 more
europepmc   +1 more source

Engineering of a sweeping antibody against IL-16 for the treatment of autoimmune diseases and cancer 2431 [PDF]

Jillian Baker, Alexander Wang, Wen-xiang Sun, Tim Luetkens   +3 more
openalex   +1 more source

CARD9 Conveys Pancreatic Islet Sympathetic Nervous β2 Signals to Reshape Macrophage Creatine Metabolism in Type 1 Diabetes

Advanced Science, EarlyView.
This study identifies CARD9 as a key mediator linking sympathetic β2‐adrenergic receptor signaling to macrophage creatine metabolism, inflammatory polarization, and neuronal integrity. Loss of β2‐AR‐PKA‐CREB1‐CARD9 signaling in macrophages reduces creatine uptake, promotes pro‐inflammatory macrophage activation, and drives sympathetic axon ferroptosis.
Huimin Yuan, Senlin Li, Shuai Liu, Hong Zhou, Yue Xu, Wenhui Li, Mengxuan Wang, Mengheng Wang, Mengzhu Zheng, Wenxi Shi, Xin Li, Yiting Feng, Ming Xiang   +12 more
wiley   +1 more source

New onset autoimmune disease following a SARS-CoV-2 infection: A systematic review protocol. [PDF]

PLoS One
Grima AA, Hiraki LT, Bolotin S, Paterson AD, Brooks JD.   +4 more
europepmc   +1 more source