Results 271 to 280 of about 9,492,165 (393)

Annexin A3 Represses Endothelial Permeability and Inflammation During Sepsis via Actin Cytoskeleton Modulation

Advanced Science, EarlyView.
Annexin A3 (ANXA3) plays an endogenous protective role in endothelial dysfunction in sepsis by stabilizing the actin cytoskeleton, modulating cell permeability, and inhibiting pATF2/CD62E inflammatory signaling. Abstract Increased endothelial permeability and a dysregulated inflammatory response play key roles in organ damage in sepsis.
Manyu Xing, Shuang Liang, Wei Cao, Qulian Guo, Wangyuan Zou   +4 more
wiley   +1 more source

The autoimmune disease risk variant NCF1-His90 is associated with a reduced risk of tuberculosis in women. [PDF]

Front Immunol
Hu X, Li S, Huang R, Fu Z, Ma C, Cheng Z, Hu H, Zhou Q, Petersen F, Yu X, Zheng J.   +10 more
europepmc   +1 more source

Development of autoimmune disease in SCID mice populated with long-term "in vitro" proliferating (NZB x NZW)F1 pre-B cells. [PDF]

, 1992
Luc Reininger, T Radaszkiewicz, Marie H. Kosco, Fritz Melchers, A Rolink   +4 more
openalex   +1 more source

DiffMC‐Gen: A Dual Denoising Diffusion Model for Multi‐Conditional Molecular Generation

Advanced Science, EarlyView.
DiffMC‐Gen, a dual‐diffusion model for 2D and 3D molecular generation, simultaneously optimizes multiple key objectives across the drug design process, enabling the generation of novel, target‐specific small‐molecule ligands with high therapeutic potential.
Yuwei Yang, Shukai Gu, Bo Liu, Xiaoqing Gong, Ruiqiang Lu, Jiayue Qiu, Xiaojun Yao, Huanxiang Liu   +7 more
wiley   +1 more source

Comprehensive systematic review and meta-analysis of the TGF-β1 T869C gene polymorphism and autoimmune disease susceptibility. [PDF]

Front Genet
Zhu Y, Qian A, Cheng Y, Li M, Huang C.
europepmc   +1 more source

A case of autoimmune hemolytic anemia associated with Graves' disease.

, 1986
Masaya MUKAI, Ichiro Watanabe, K. Tanimura, Masato Shimizu, Ichiro Oki, Katsunori Ohnishi, Atsushi Fujisaku, Hôji SUZUKI, Shôichi NAKAGAWA, Akira Sagawa   +9 more
openalex   +2 more sources

Gender differences in autoimmune disease

Frontiers in neuroendocrinology (Print), 2014
S. Ngo, F. Steyn, P. Mccombe, P. Mccombe
semanticscholar   +1 more source

KK2DP7 Stimulates CD11b+ Cell Populations in the Spleen to Elicit Trained Immunity for Anti‐Tumor Therapy

Advanced Science, EarlyView.
This study introduces KK2DP7, a dendrimer‐structured peptide adjuvant, as a tool to decode trained immunity's role in antitumor therapy. Splenic CD11b+ cells mediate tumor suppression via TLR2‐IRF7 activation and epigenetic reprogramming, validated by adoptive transfer experiments.
Rui Zhang, Lin Tang, Yusi Wang, Xuejing Zhou, Zhenyu Ding, Li Yang   +5 more
wiley   +1 more source

ROS-dependent SOCS3 upregulation disrupts regulatory T cell stability during autoimmune disease development. [PDF]

Redox Biol
Satooka H, Nakamura Y, Hirata T.
europepmc   +1 more source

Studies on Precipitating Antibodies to Solubilized Thyroid Membrane Antigens by Gel Immunodiffusion in Autoimmune Thyroid Diseases

, 1981
S Hirakawa
openalex   +2 more sources